Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.41 |
| ▸ | SELL | P14151 | 1/20 | 0.36 |
| ▸ | SELP | P16109 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2990213 | 0.88 | XDH (0.44) | XDHSLC22A12SELLSELPKDM4E | |
| SCHEMBL17201308 | 0.77 | GRM1 (0.47) | XDHSLC22A12SELLSELPKDM4E | |
| SCHEMBL3111073 | 0.77 | AR (0.42) | XDHSLC22A12KDM4EHSD17B10 | |
| SCHEMBL3805126 | 0.74 | DPP4 (0.47) | SELLSELPKDM4EHSD17B10GRM1 | |
| SCHEMBL27666816 | 0.74 | XDH (0.38) | XDHSLC22A12KDM4EHSD17B10 | |
| SCHEMBL26613167 | 0.73 | MAPT (0.51) | XDHSLC22A12 | |
| SCHEMBL23699537 | 0.72 | XDH (0.37) | XDHSLC22A12KDM4EHSD17B10 | |
| SCHEMBL3455993 | 0.72 | NOTUM (0.49) | XDHSLC22A12 | |
| SCHEMBL28153672 | 0.70 | CYP1A2 (0.56) | XDHSLC22A12KDM4EHSD17B10 | |
| SCHEMBL2427288 | 0.70 | MAPT (0.44) | XDHSLC22A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140121362-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | MICHIGAN DIAGNOSTICS, LLC (US) | 2014-05-01 | — | — | US | disclosed |
| US-8546150-B2 | Ultra-sensitive chemiluminescent substrates for enzymes and their conjugates | Michigan Diagnostics, L.L.C. (US) | 2013-10-01 | — | — | US | disclosed |
| US-20100317031-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-20100317122-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | GIRI BRIJ PAL | 2010-12-16 | — | — | US | disclosed |
| US-7781229-B2 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC (US) | 2010-08-24 | — | — | US | disclosed |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | MICHIGAN DIAGNOSTICS, LLC | 2007-09-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140121362-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | XDH 2/4885SLC22A12 3184/4885SELL 1562/4885 |
| US-20070225498-A1 | water-soluble, stable in aqueous buffers, for use in biological assaying include acridane-based compounds and (1,2)-dioxetanes; used in the detection of antibodies or antigen in biological fluids and for compounds, particularly toxins and contaminants in the environment and food. | BTD, DDT, LPO | XDH 37/4885SLC22A12 1775/4885SELL 2044/4885 |
| US-20100317031-A1 | ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, MPO | XDH 2/4885SLC22A12 3443/4885SELL 1722/4885 |
| US-20100317122-A1 | NEW ULTRA-SENSITIVE CHEMILUMINESCENT SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES | DUOX1, XDH, LPO | XDH 2/4885SLC22A12 3661/4885SELL 1731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.