Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HRH2 | P25021 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | NLRP3 | Q96P20 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29809072 | 0.89 | L3MBTL1 (0.46) | KCNH2L3MBTL1MAOBSMN1; SMN2PDE4A | |
| SCHEMBL24732579 | 0.84 | TLR7 (0.54) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL29808887 | 0.84 | TLR7 (0.54) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL3188618 | 0.80 | TLR7 (0.67) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL29976933 | 0.79 | TLR7 (0.54) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL29809062 | 0.79 | NLRP3 (0.52) | TLR7KCNH2NLRP3L3MBTL1TLR8 | |
| SCHEMBL24732755 | 0.79 | NLRP3 (0.52) | TLR7KCNH2NLRP3L3MBTL1TLR8 | |
| SCHEMBL24732578 | 0.79 | HRH3 (0.50) | TLR7PDE4DLMNAPOLBHRH2 | |
| Hydrochloric Acid SCHEMBL3197884 | 0.79 | TLR7 (0.66) | TLR7PDE4DLMNAPOLBHRH2 | |
| SCHEMBL24732765 | 0.76 | TLR7 (0.57) | TLR7PDE4DLMNAPOLBHRH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |