Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 7/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29977295 | 0.89 | TLR7 (0.48) | L3MBTL1MAOBKCNH2SMN1; SMN2PDE4A | |
| SCHEMBL24733009 | 0.84 | MAOB (0.48) | MAOBSMN1; SMN2MAPK1HTR6 | |
| SCHEMBL29808930 | 0.84 | MAOB (0.48) | MAOBSMN1; SMN2MAPK1HTR6 | |
| SCHEMBL9601993 | 0.81 | CYP11B1 (0.50) | KCNH2SMN1; SMN2MAPK1PDE4AHTT | |
| SCHEMBL29977341 | 0.79 | MC4R (0.47) | MAOBHTR6 | |
| SCHEMBL29808996 | 0.79 | KCNH2 (0.46) | L3MBTL1MAOBKCNH2HTR6 | |
| SCHEMBL24732627 | 0.79 | KCNH2 (0.46) | L3MBTL1MAOBKCNH2HTR6 | |
| SCHEMBL24732850 | 0.79 | HRH3 (0.50) | L3MBTL1MAOBSMN1; SMN2MAPK1 | |
| SCHEMBL29977334 | 0.76 | HTT (0.42) | MAOBKCNH2SMN1; SMN2MAPK1HTR6 | |
| SCHEMBL29977138 | 0.74 | MAOB (0.41) | MAOBSMN1; SMN2HTR6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022161420-A1 | CLASS OF HETEROAROMATIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 上海翊石医药科技有限公司 | 2022-08-04 | — | — | WO | disclosed |
| CN-114805341-A | Aromatic heterocyclic compounds and preparation method and application thereof | 上海翊石医药科技有限公司 | 2022-07-29 | — | — | CN | disclosed |