Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 3/20 | 0.38 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.38 |
| ▸ | GRIA3 | P42263 | 3/20 | 0.38 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.38 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.38 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.38 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.38 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.38 |
| ▸ | SPR | P35270 | 2/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.33 |
| ▸ | RPA1 | P27694 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898513 | 0.77 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GGRIA1GRIA2GRIA3 | |
| SCHEMBL14864846 | 0.74 | PARP1 (0.40) | PDPK1KDM4E | |
| SCHEMBL29976892 | 0.67 | CA12 (0.45) | KDM4E | |
| SCHEMBL25372948 | 0.67 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GGRIA1GRIA2GRIA3 | |
| SCHEMBL3459056 | 0.67 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 | |
| SCHEMBL12756983 | 0.67 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 | |
| SCHEMBL29079139 | 0.67 | APOBEC3A (0.49) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 | |
| SCHEMBL1665456 | 0.65 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 | |
| SCHEMBL18372931 | 0.65 | APOBEC3A (0.46) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 | |
| SCHEMBL28410772 | 0.64 | APOBEC3A (0.45) | APOBEC3AAPOBEC3GSPRKDM4ERPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | QDPR, SIRT5, PDXK | APOBEC3A 2893/4885APOBEC3G 3148/4885GRIA1 4072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.