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Spinorphin

Spinorphin

SCHEMBL29977609

CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C)C(C)C

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.60
▸ SLC6A2 P23975 1/20 0.59
▸ DPP3 Q9NY33 5/20 0.59
▸ CAPN1 P07384 2/20 0.58
▸ CTSB P07858 2/20 0.58
▸ REN P00797 2/20 0.57
▸ OPRM1 P35372 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spinorphin SCHEMBL25273730 1.00 KISS1R (0.60) KISS1RSLC6A2DPP3CAPN1CTSB
Spinorphin SCHEMBL25217672 1.00 KISS1R (0.60) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392074 0.98 KISS1R (0.58) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392472 0.98 KISS1R (0.58) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392261 0.94 DPP3 (0.61) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392155 0.91 CAPN1 (0.59) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30844089 0.89 KISS1R (0.64) KISS1RSLC6A2OPRM1
SCHEMBL29471736 0.89 SLC6A2 (0.63) SLC6A2DPP3CAPN1CTSBOPRM1
SCHEMBL29350618 0.89 SLC6A2 (0.63) SLC6A2DPP3CAPN1CTSBOPRM1
SCHEMBL31332280 0.88 KISS1R (0.64) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4426280-B1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS GURBA ALEXANDRE (CH) 2026-03-18 — — EP claimed
US-20240335379-A1 STABLE PHARMACEUTICAL COMPOSITIONS OF APOMORPHINE ZYDUS LIFESCIENCES LIMITED (IN) 2024-10-10 — — US disclosed
CN-109414402-B Method for preparing a drug delivery system with a testosterone compound present externally or topically and such a drug delivery system EB IP希博里塔布斯有限责任公司 2022-11-04 — — CN disclosed
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