Spinorphin

Spinorphin

SCHEMBL25217672

CC(C)C[C@H](N)C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@H](C(=O)O)[C@@H](C)O)C(C)C)C(C)C

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 5/20 0.60
▸ SLC6A2 P23975 1/20 0.59
▸ DPP3 Q9NY33 5/20 0.59
▸ CAPN1 P07384 2/20 0.58
▸ CTSB P07858 2/20 0.58
▸ REN P00797 2/20 0.57
▸ OPRM1 P35372 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spinorphin SCHEMBL29977609 1.00 KISS1R (0.60) KISS1RSLC6A2DPP3CAPN1CTSB
Spinorphin SCHEMBL25273730 1.00 KISS1R (0.60) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392074 0.98 KISS1R (0.58) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392472 0.98 KISS1R (0.58) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392261 0.94 DPP3 (0.61) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30392155 0.91 CAPN1 (0.59) KISS1RSLC6A2DPP3CAPN1CTSB
SCHEMBL30844089 0.89 KISS1R (0.64) KISS1RSLC6A2OPRM1
SCHEMBL29471736 0.89 SLC6A2 (0.63) SLC6A2DPP3CAPN1CTSBOPRM1
SCHEMBL29350618 0.89 SLC6A2 (0.63) SLC6A2DPP3CAPN1CTSBOPRM1
SCHEMBL31332280 0.88 KISS1R (0.64) KISS1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS 4TEEN4 Pharmaceuticals GmbH (DE) 2026-03-26 — — US disclosed
EP-4426280-B1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS GURBA ALEXANDRE (CH) 2026-03-18 — — EP disclosed
US-20250057791-A1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS GURBA ALEXANDRE (CH) 2025-02-20 — — US disclosed
US-20240385197-A1 METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS 4TEEN4 Pharmaceuticals GmbH (DE) 2024-11-21 — — US disclosed
EP-4197533-A1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS Guerin, Patrick (CH) 2023-06-21 — — EP disclosed
CN-108220246-B Compounds for improving viral transduction 蓝鸟生物公司 2022-07-12 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083672-A1 FORMULATIONS AND DOSAGE AMOUNTS FOR ADMINISTERING AN ANTI-DPP3 ANTIBODY OR FRAGMENT THEREOF TO HUMANS DPP3, DPP4, TREH KISS1R 4710/4885SLC6A2 372/4885DPP3 1/4885
US-20240385197-A1 METHODS FOR DETERMINING DPP3 AND THERAPEUTIC METHODS DPP3, DPP4, DPP7 KISS1R 1726/4885SLC6A2 847/4885DPP3 1/4885
US-20250057791-A1 PROTECTION AGAINST ARTHROPOD PARASITES WITH PURINERGIC RECEPTOR (OPR) ANTAGONISTS P2RX2, P2RX3, P2RX1 KISS1R 473/4885SLC6A2 748/4885DPP3 1395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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