Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 2/20 | 0.46 |
| ▸ | TNKS | O95271 | 8/20 | 0.41 |
| ▸ | PARP1 | P09874 | 2/20 | 0.41 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.38 |
| ▸ | PDE2A | O00408 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112528 | 1.00 | PTGER3 (0.46) | PTGER3TNKSPARP1TNKS2PDE3B | |
| Hydrochloric Acid SCHEMBL23112585 | 0.99 | PTGER3 (0.45) | PTGER3TNKSPARP1TNKS2PDE3B | |
| Hydrochloric Acid SCHEMBL29977490 | 0.99 | PTGER3 (0.45) | PTGER3TNKSPARP1TNKS2PDE3B | |
| SCHEMBL29978023 | 0.89 | ADORA3 (0.43) | PTGER3TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL23112707 | 0.89 | ADORA3 (0.43) | PTGER3TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL23112899 | 0.84 | TOP2A (0.46) | TNKSPARP1TNKS2ALDH1A1 | |
| SCHEMBL29977747 | 0.83 | TACR3 (0.40) | PTGER3PDE2A | |
| SCHEMBL28556428 | 0.83 | TACR3 (0.40) | PTGER3PDE2A | |
| SCHEMBL28556425 | 0.83 | TACR3 (0.40) | PTGER3PDE2A | |
| SCHEMBL23112456 | 0.79 | PTGER3 (0.42) | PTGER3TNKSPARP1TNKS2PDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | QDPR, SIRT5, PDXK | PTGER3 223/4885TNKS 1312/4885PARP1 415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.