Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 14/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29978488 | 0.91 | NPC1 (0.39) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL29979015 | 0.91 | MEN1 (0.47) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL29978402 | 0.91 | NPC1 (0.47) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL29977966 | 0.91 | NAMPT (0.43) | MAPTHDAC4HDAC6 | |
| SCHEMBL29978688 | 0.90 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2MAPTHDAC4 | |
| SCHEMBL29977979 | 0.90 | HDAC4 (0.47) | KMT2ARAB9ANPC1SMN1; SMN2HDAC4 | |
| SCHEMBL29978134 | 0.87 | EPHX2 (0.45) | MAPT | |
| SCHEMBL29979201 | 0.86 | GPR142 (0.45) | KMT2ARAB9ANPC1SMN1; SMN2MAPT | |
| SCHEMBL29977806 | 0.85 | HDAC6 (0.37) | HDAC4HDAC6HDAC8HDAC2HDAC1 | |
| SCHEMBL29978286 | 0.85 | CYP3A4 (0.44) | KMT2ARAB9ANPC1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | claimed |
| WO-2022234470-A1 | NOVEL FUSED HETEROCYCLIC COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI | PI INDUSTRIES LTD. (IN) | 2022-11-10 | — | — | WO | disclosed |