Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29979685 | 0.86 | MCOLN2 (0.57) | MCOLN2PAX8MAPTHTTALDH1A1 | |
| SCHEMBL23043735 | 0.86 | MCOLN2 (0.57) | MCOLN2PAX8MAPTHTTALDH1A1 | |
| SCHEMBL23057166 | 0.83 | MCOLN3 (0.52) | MCOLN2HTTSMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL29979661 | 0.76 | GAA (0.51) | MCOLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29978619 | 0.75 | MCOLN2 (0.77) | MCOLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23057222 | 0.75 | ALDH1A1 (0.49) | MCOLN2MAPTHTTALDH1A1MEN1 | |
| SCHEMBL23379508 | 0.75 | MCOLN3 (0.56) | MCOLN2HTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL23057145 | 0.73 | L3MBTL1 (0.53) | MCOLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL29979001 | 0.72 | MCOLN2 (0.47) | MCOLN2MAPTHTTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23043701 | 0.72 | L3MBTL1 (0.49) | MCOLN2MAPTHTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | MCOLN2 2/4885PAX8 2704/4885MAPT 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.