Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.65 |
| ▸ | CCR5 | P51681 | 1/20 | 0.65 |
| ▸ | CCR8 | P51685 | 1/20 | 0.65 |
| ▸ | LOXL2 | Q9Y4K0 | 12/20 | 0.55 |
| ▸ | LOX | P28300 | 4/20 | 0.55 |
| ▸ | LOXL3 | P58215 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | NOS2 | P35228 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Perchlorate SCHEMBL9339609 | 0.90 | CCR1 (0.53) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL352525 | 0.88 | LOXL2 (0.61) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL352289 | 0.85 | CCR1 (0.61) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL23037127 | 0.84 | CCR1 (0.71) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL15082607 | 0.84 | CCR1 (0.71) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL29693673 | 0.84 | CCR1 (0.71) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL21377079 | 0.83 | LOXL2 (0.46) | CCR1CCR5CCR8LOXL2LOX | |
| Dipyridyl SCHEMBL8102799 | 0.83 | CCR1 (0.45) | CCR1CCR5CCR8LOXL2LOX | |
| SCHEMBL8425645 | 0.82 | CCR1 (0.68) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL7039186 | 0.82 | CCR1 (0.57) | CCR1CCR5CCR8LOXL2LOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253718-B | Organic compound modified by lonidamine, cyclometallated complex based on organic compound, preparation method and application thereof | 南京师范大学 | 2025-01-14 | — | — | CN | claimed |
| CN-116082413-B | Pterostilbene modified cyclometalated iridium (III) complex and preparation method and application thereof | 南京师范大学 | 2024-12-10 | — | — | CN | claimed |
| CN-117946184-A | Cyclometallation complex with tail connected anticancer/anti-metastasis active molecules and preparation method and application thereof | 南京师范大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117756859-A | alpha-TOS modified cyclometalated iridium (III) complex and synthesis method and application thereof | 南京师范大学 | 2024-03-26 | — | — | CN | claimed |
| CN-117343104-A | Cyclometalated iridium (III) complex modified by lichenic acid and synthesis method and application thereof | 南京师范大学 | 2024-01-05 | — | — | CN | claimed |
| CN-115160376-B | Cinnamic acid modified cyclometalated iridium (III) complex and synthetic method and application thereof | 南京师范大学 | 2023-11-21 | — | — | CN | claimed |
| CN-116253718-A | Organic compound modified by lonidamine, cyclometallated complex based on organic compound, preparation method and application thereof | 南京师范大学 | 2023-06-13 | — | — | CN | claimed |
| CN-116253773-A | Metal complex with tail connected with immunocompetent molecules as well as preparation method and application thereof | 南京师范大学 | 2023-06-13 | — | — | CN | claimed |
| CN-116082413-A | Pterostilbene modified cyclometalated iridium (III) complex and preparation method and application thereof | 南京师范大学 | 2023-05-09 | — | — | CN | claimed |
| CN-115160376-A | Cinnamic acid modified cyclometalated iridium (III) complex and synthesis method and application thereof | 南京师范大学 | 2022-10-11 | — | — | CN | claimed |
| CN-116253718-B | Organic compound modified by lonidamine, cyclometallated complex based on organic compound, preparation method and application thereof | 南京师范大学 | 2025-01-14 | — | — | CN | disclosed |
| CN-116082413-B | Pterostilbene modified cyclometalated iridium (III) complex and preparation method and application thereof | 南京师范大学 | 2024-12-10 | — | — | CN | disclosed |
| CN-117946184-A | Cyclometallation complex with tail connected anticancer/anti-metastasis active molecules and preparation method and application thereof | 南京师范大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117756859-A | alpha-TOS modified cyclometalated iridium (III) complex and synthesis method and application thereof | 南京师范大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117343104-A | Cyclometalated iridium (III) complex modified by lichenic acid and synthesis method and application thereof | 南京师范大学 | 2024-01-05 | — | — | CN | disclosed |
| CN-115160376-B | Cinnamic acid modified cyclometalated iridium (III) complex and synthetic method and application thereof | 南京师范大学 | 2023-11-21 | — | — | CN | disclosed |
| CN-116253718-A | Organic compound modified by lonidamine, cyclometallated complex based on organic compound, preparation method and application thereof | 南京师范大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-116253773-A | Metal complex with tail connected with immunocompetent molecules as well as preparation method and application thereof | 南京师范大学 | 2023-06-13 | — | — | CN | disclosed |
| CN-116082413-A | Pterostilbene modified cyclometalated iridium (III) complex and preparation method and application thereof | 南京师范大学 | 2023-05-09 | — | — | CN | disclosed |
| CN-115160376-A | Cinnamic acid modified cyclometalated iridium (III) complex and synthesis method and application thereof | 南京师范大学 | 2022-10-11 | — | — | CN | disclosed |