Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057183 | 1.00 | ALDH1A1 (0.48) | ALDH1A1MCOLN2LMNAPOLBGAA | |
| SCHEMBL29979144 | 0.91 | ALDH1A1 (0.56) | ALDH1A1MCOLN2LMNAPOLBGAA | |
| SCHEMBL29979154 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MCOLN2LMNAMEN1KMT2A | |
| SCHEMBL23057150 | 0.86 | ALDH1A1 (0.48) | ALDH1A1MCOLN2LMNAMEN1KMT2A | |
| SCHEMBL23057145 | 0.85 | L3MBTL1 (0.53) | ALDH1A1MCOLN2LMNAPOLBGAA | |
| SCHEMBL23057173 | 0.82 | MCOLN2 (0.44) | ALDH1A1MCOLN2LMNAGAAMEN1 | |
| SCHEMBL29978499 | 0.82 | MCOLN2 (0.44) | ALDH1A1MCOLN2LMNAGAAMEN1 | |
| SCHEMBL29979661 | 0.81 | GAA (0.51) | ALDH1A1MCOLN2LMNAPOLBGAA | |
| SCHEMBL23057226 | 0.81 | ALDH1A1 (0.55) | ALDH1A1MCOLN2LMNAPOLBGAA | |
| SCHEMBL24871275 | 0.81 | L3MBTL1 (0.55) | ALDH1A1MCOLN2LMNAPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | ALDH1A1 1368/4885MCOLN2 2/4885LMNA 581/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.