Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.42 |
| ▸ | MCOLN2 | Q8IZK6 | 2/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SQSTM1 | Q13501 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23057150 | 1.00 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTCRHBPCRHR2 | |
| SCHEMBL23057183 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTLMNAMCOLN2 | |
| SCHEMBL29979147 | 0.86 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MAPTLMNAMCOLN2 | |
| SCHEMBL23057145 | 0.82 | L3MBTL1 (0.53) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL29979144 | 0.80 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL23057187 | 0.80 | ALDH1A1 (0.67) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL23057226 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL23057334 | 0.79 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL24871275 | 0.79 | L3MBTL1 (0.55) | ALDH1A1MAPTLMNAHPGDMCOLN2 | |
| SCHEMBL29978639 | 0.79 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES | 2022-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220315548-A1 | SMALL MOLECULE AGONISTS OF MUCOLIPIN 1 AND USES THEREOF | MCOLN1, MCOLN2, MCOLN3 | ALDH1A1 1368/4885SMN1; SMN2 41/4885MAPT 3427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.