Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12381475 | 1.00 | AMY1A (0.39) | AMY1AMAPTKDM4ERAB9AS1PR4 | |
| SCHEMBL19407002 | 0.82 | KDM4E (0.40) | MAPTKDM4ERAB9AS1PR4HSP90AA1 | |
| SCHEMBL31571429 | 0.79 | CYP1A1 (0.40) | MAPTKDM4ERAB9APOLBTDP1 | |
| SCHEMBL3751809 | 0.79 | CYP1A1 (0.40) | MAPTKDM4ERAB9APOLBTDP1 | |
| SCHEMBL1494033 | 0.77 | MAPT (0.38) | MAPTKDM4ERAB9APOLBTDP1 | |
| SCHEMBL8990966 | 0.77 | HTR2A (0.43) | AMY1AMAPTKDM4ERAB9AS1PR4 | |
| SCHEMBL3841837 | 0.77 | NQO2 (0.37) | MAPTKDM4EMAPK1HTTAPOBEC3G | |
| SCHEMBL16704713 | 0.77 | MAPT (0.43) | AMY1AMAPTKDM4ERAB9AS1PR4 | |
| SCHEMBL27731713 | 0.77 | KDM4E (0.37) | MAPTKDM4ERAB9AS1PR4HSP90AA1 | |
| SCHEMBL3837168 | 0.77 | ALDH1A1 (0.33) | KDM4EG6PDMAPK1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115286605-B | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide alternative source | 武汉大学 | 2024-04-09 | — | — | CN | disclosed |
| CN-115594582-A | Synthesis of 13 Method and application of C-marked 4-trifluoromethyl aryl formate | 武汉大学（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-115286605-A | Method for synthesizing isochromanone compounds based on carbon monoxide gas or carbon monoxide substitute source | 武汉大学 | 2022-11-04 | — | — | CN | disclosed |