Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | MAOB | P27338 | 2/20 | 0.52 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.49 |
| ▸ | MIF | P14174 | 4/20 | 0.49 |
| ▸ | CD74 | P04233 | 1/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749452 | 0.90 | MAOA (0.61) | MAOAMAOBHSP90AB1MIFCD74 | |
| SCHEMBL22749405 | 0.80 | L3MBTL1 (0.46) | MAOAMAOBHSP90AB1MIFCD74 | |
| SCHEMBL29980445 | 0.78 | PTPN1 (0.45) | MAOAMAOBMIFCA12CA9 | |
| SCHEMBL29980598 | 0.78 | PTPN1 (0.45) | MAOAMAOBMIFCA12CA9 | |
| SCHEMBL29548308 | 0.75 | MAOA (0.57) | MAOAMAOBMIFCA12CA9 | |
| SCHEMBL19876876 | 0.73 | HSP90AB1 (0.46) | MAOAMAOBHSP90AB1MIFCD74 | |
| SCHEMBL28701789 | 0.71 | HSP90AB1 (0.40) | MAOAMAOBHSP90AB1MIFCD74 | |
| SCHEMBL29980293 | 0.70 | MAOA (0.57) | MAOAMAOBMIFCA12CA9 | |
| SCHEMBL19876924 | 0.69 | HDAC3 (0.44) | HSP90AB1MIFCD74CA12CA9 | |
| SCHEMBL23646735 | 0.69 | HDAC3 (0.44) | HSP90AB1MIFCD74CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220299521-A1 | CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE | Indian Institute Of Science Education And Research Bhopal (IN) | 2022-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220299521-A1 | CHEMOSELECTIVE SENSITIVITY BOOSTER FOR TAGGING A PEPTIDE, PEPTIDE CONJUGATE, OR SIMILAR REACTIVE MOLECULE | PTMS, PA2G4, MAX | MAOA 4551/4885MAOB 3989/4885HSP90AB1 594/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.