Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.57 |
| ▸ | DDX3X | O00571 | 2/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 4/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17978468 | 0.81 | NOTUM (0.53) | MAOAMAOBDDX3XNOTUMCA1 | |
| SCHEMBL20046238 | 0.78 | MAOA (0.68) | MAOAMAOBNOTUMCA1CA2 | |
| SCHEMBL16401559 | 0.78 | NOTUM (0.74) | MAOADDX3XNOTUMCA1CA2 | |
| SCHEMBL22873389 | 0.76 | MAOA (0.64) | MAOAMAOBNOTUMCA1CA2 | |
| SCHEMBL17978570 | 0.75 | PTGS2 (0.50) | DDX3XNOTUMCA1CA2CA9 | |
| SCHEMBL29979916 | 0.75 | MAOA (0.52) | MAOAMAOBNOTUMCA1CA2 | |
| SCHEMBL16964546 | 0.75 | DDX3X (0.53) | MAOAMAOBDDX3XNOTUMMIF | |
| SCHEMBL15060983 | 0.71 | MIF (0.68) | DDX3XNOTUMCA1CA2CA9 | |
| SCHEMBL29828549 | 0.71 | MAOA (0.66) | MAOAMAOBDDX3XMIFP2RX7 | |
| SCHEMBL17185566 | 0.71 | NOTUM (0.59) | NOTUMCA1CA2CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3258929-B1 | FACTOR IXA INHIBITORS | MERCK SHARP & DOHME (US) | 2022-04-27 | — | — | EP | claimed |