Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.72 |
| ▸ | AKR1C3 | P42330 | 7/20 | 0.59 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.59 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.59 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CDC42 | P60953 | 1/20 | 0.56 |
| ▸ | RAC1 | P63000 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28346869 | 1.00 | ABCB11 (0.72) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL11998984 | 0.87 | ABCB11 (0.56) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL9167387 | 0.86 | ALDH1A1 (0.53) | ABCB11AKR1C3AKR1C2AKR1C1TSHR | |
| SCHEMBL9630941 | 0.86 | ABCB11 (0.68) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| Naproxol SCHEMBL10395753 | 0.84 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| Naproxol SCHEMBL30599771 | 0.84 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| Naproxol SCHEMBL29979997 | 0.84 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL13803017 | 0.84 | ABCB11 (0.70) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| SCHEMBL8474842 | 0.84 | ABCB11 (0.70) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 | |
| Naproxol SCHEMBL43203 | 0.84 | ABCB11 (1.00) | ABCB11AKR1C3AKR1C2PTGS1AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230167059-A1 | AMINO ACID DERIVATIVE CONTAINING NON-STEROIDAL ANTI-INFLAMMATORY DRUG STRUCTURE AND PREPARATION METHOD AND APPLICATION THEREOF | JIANGSU PROTELIGHT PHARMACEUTICAL & BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
| CN-110655456-B | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-11-24 | — | — | CN | disclosed |
| CN-110655456-A | Method for preparing chiral alkyl compound by asymmetric catalytic hydrogenation of E/Z mixed or single-configuration tri-substituted olefin | 浙江大学 | 2020-01-07 | — | — | CN | disclosed |
| US-9896587-B2 | Planarizing agents and devices | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2018-02-20 | — | — | US | disclosed |
| US-20140299858-A1 | PLANARIZING AGENTS AND DEVICES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-10-09 | — | — | US | disclosed |
| US-8709291-B2 | Planarizing agents and devices | PLEXTRONICS, INC. (US) | 2014-04-29 | — | — | US | disclosed |
| US-20120277367-A1 | PLANARIZING AGENTS AND DEVICES | PLEXTRONICS, INC. | 2012-11-01 | — | — | US | disclosed |
| US-8187501-B2 | Planarizing agents and devices | PLEXTRONICS, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20100072462-A1 | PLANARIZING AGENTS AND DEVICES | PLEXTRONICS, INC. | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230167059-A1 | AMINO ACID DERIVATIVE CONTAINING NON-STEROIDAL ANTI-INFLAMMATORY DRUG STRUCTURE AND PREPARATION METHOD AND APPLICATION THEREOF | IL4I1, TNF, AADAT | ABCB11 1827/4885AKR1C3 1139/4885AKR1C2 905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.