Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049291 | 0.79 | — | — | |
| SCHEMBL9789419 | 0.79 | — | — | |
| SCHEMBL9049283 | 0.79 | — | — | |
| SCHEMBL8093065 | 0.77 | SLC28A3 (0.34) | — | |
| SCHEMBL18259481 | 0.76 | — | — | |
| SCHEMBL27863829 | 0.76 | ALDH1A1 (0.35) | LMNA | |
| SCHEMBL2589085 | 0.76 | — | — | |
| SCHEMBL27970168 | 0.74 | TSHR (0.33) | — | |
| SCHEMBL9093991 | 0.74 | — | — | |
| SCHEMBL9538329 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2193789-B1 | The application of 3,5-dihydroxytoluene or derivatives thereof in the preparation of medicine and functional food for treating or preventing depression | KUNMING INST BOTANY CN ACAD (CN) | 2013-02-20 | — | — | EP | claimed |
| US-20100190730-A1 | APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2010-07-29 | — | — | US | claimed |
| EP-2193789-A1 | THE APPLICATION OF 3, 5-DIHYDROXYTOLUENE OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINE AND FUNCTIONAL FOR TREATING OR PREVENTING DEPRESSION. | Kunming Institute Of Botany, Chinese Academy Of Sciences (CN) | 2010-06-09 | — | — | EP | claimed |
| US-8859508-B2 | Application of 5-methyl-1,3-benzenediol or derivatives thereof in the preparation of medicines and functional foods for treatment or prevention of depression | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2014-10-14 | — | — | US | disclosed |
| EP-2193789-B1 | The application of 3,5-dihydroxytoluene or derivatives thereof in the preparation of medicine and functional food for treating or preventing depression | KUNMING INST BOTANY CN ACAD (CN) | 2013-02-20 | — | — | EP | disclosed |
| CN-101742992-B | The application of 5-methyl-1,3-benzenediol or derivatives thereof in the preparation of medicines and functional foods for treatment or prevention of depression | KUNMING INST BOTANY CN ACAD | 2013-01-23 | — | — | CN | disclosed |
| US-20100190730-A1 | APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION | KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCES (CN) | 2010-07-29 | — | — | US | disclosed |
| EP-2193789-A1 | THE APPLICATION OF 3, 5-DIHYDROXYTOLUENE OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINE AND FUNCTIONAL FOR TREATING OR PREVENTING DEPRESSION. | Kunming Institute Of Botany, Chinese Academy Of Sciences (CN) | 2010-06-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100190730-A1 | APPLICATION OF 5-METHYL-1,3-BENZENEDIOL OR DERIVATIVES THEREOF IN THE PREPARATION OF MEDICINES AND FUNCTIONAL FOODS FOR TREATMENT OR PREVENTION OF DEPRESSION | TPH1, TPH2, HTR5A | LMNA 597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.