SCHEMBL29981946

SCHEMBL29981946

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)N)C(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)[C@@H](C)CC

nearest known ligand 0.59

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ KISS1R Q969F8 11/20 0.59
▸ IL23R Q5VWK5 6/20 0.57
▸ GLP1R P43220 2/20 0.56
▸ ECE1 P42892 1/20 0.56
▸ MUS81 Q96NY9 1/20 0.56
▸ PTH1R Q03431 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29981974 1.00 KISS1R (0.59) KISS1RIL23RGLP1RECE1MUS81
SCHEMBL29982283 0.98 KISS1R (0.62) KISS1RIL23R
SCHEMBL30401709 0.98 KISS1R (0.62) KISS1RIL23R
SCHEMBL30401759 0.96 KISS1R (0.61) KISS1RIL23RGLP1RECE1MUS81
SCHEMBL29981789 0.89 IL23R (0.58) KISS1RIL23R
SCHEMBL30974278 0.88 IL23R (0.62) IL23RGLP1RECE1MUS81
SCHEMBL29982290 0.88 KISS1R (0.54) KISS1RIL23R
SCHEMBL29982442 0.88 KISS1R (0.54) KISS1RIL23R
SCHEMBL30339295 0.88 CCKBR (0.62) IL23RGLP1RECE1MUS81PTH1R
SCHEMBL29415985 0.87 KISS1R (0.64) KISS1RGLP1RECE1MUS81

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR PHARMACEUTICALS CO., LTD. (JP) 2023-06-29 — — US claimed
EP-4108676-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR Pharmaceuticals Co., Ltd. (JP) 2022-12-28 — — EP claimed
CN-115151556-A Human transferrin receptor binding peptides JCR制药股份有限公司 2022-10-04 — — CN claimed
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-11-28 — — US disclosed
EP-4389893-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE Takeda Pharmaceutical Company Limited (JP) 2024-06-26 — — EP disclosed
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR PHARMACEUTICALS CO., LTD. (JP) 2023-06-29 — — US disclosed
WO-2023026994-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE 武田薬品工業株式会社 2023-03-02 — — WO disclosed
EP-4108676-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE JCR Pharmaceuticals Co., Ltd. (JP) 2022-12-28 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240390508-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE MUSK, TFRC, SLC7A1 KISS1R 2887/4885IL23R 2841/4885GLP1R 1459/4885
US-20230203098-A1 HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE TFRC, SLC3A2, SLC7A1 KISS1R 1171/4885IL23R 1413/4885GLP1R 596/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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