Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CLK2 | P49760 | 5/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.38 |
| ▸ | HCK | P08631 | 1/20 | 0.38 |
| ▸ | ROS1 | P08922 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PRKACA | P17612 | 1/20 | 0.38 |
| ▸ | MARK3 | P27448 | 1/20 | 0.38 |
| ▸ | LTK | P29376 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | MAP3K10 | Q02779 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31324521 | 0.99 | TSHR (0.44) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL24394594 | 0.98 | TSHR (0.43) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL24394451 | 0.98 | TSHR (0.43) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL26626202 | 0.93 | FADS1 (0.39) | TSHRLMNACLK2JAK2ROCK2 | |
| SCHEMBL31324566 | 0.87 | ALDH1A1 (0.43) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL29985766 | 0.86 | KDM4E (0.47) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL31324558 | 0.86 | ALDH1A1 (0.43) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL29986178 | 0.85 | TSHR (0.45) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL29985503 | 0.85 | TSHR (0.45) | TSHRALDH1A1LMNAKDM4EHTT | |
| SCHEMBL29985420 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1LMNAKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12291519-B2 | 2-hydroxycycloalkane-1-carbamoyl | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-05-06 | — | — | US | disclosed |
| EP-4013751-B1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-01-22 | — | — | EP | disclosed |
| US-20220324847-A1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | IDORSIA PHARMACEUTICALS LTD (CH) | 2022-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12291519-B2 | 2-hydroxycycloalkane-1-carbamoyl | LGALS1, LGALS2, LGALS3 | TSHR 1202/4885ALDH1A1 657/4885LMNA 772/4885 |
| US-20220324847-A1 | 2-HYDROXYCYCLOALKANE-1-CARBAMOYL DERIVATIVES | LGALS1, LGALS2, LGALS3 | TSHR 1262/4885ALDH1A1 807/4885LMNA 571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.