Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | UBE2N | P61088 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16235127 | 1.00 | HSD11B1 (0.47) | HSD11B1HSP90AA1HSP90AB1HPGDTDP1 | |
| SCHEMBL16235419 | 0.83 | KDM4E (0.56) | CA1CA2KDM4ETSHRPTK2B | |
| SCHEMBL16235284 | 0.83 | HSP90AA1 (0.52) | HSD11B1HSP90AA1HSP90AB1HPGDALDH1A1 | |
| SCHEMBL16235417 | 0.82 | SLC40A1 (0.51) | CA1CA2ALDH1A1KDM4ETSHR | |
| SCHEMBL16235275 | 0.76 | HSD11B1 (0.47) | HSD11B1HSP90AA1HSP90AB1HPGDTDP1 | |
| SCHEMBL16235261 | 0.75 | CCR4 (0.46) | HSD11B1HPGDTDP1UBE2NL3MBTL1 | |
| SCHEMBL16235619 | 0.74 | GLO1 (0.48) | PGR | |
| SCHEMBL16235784 | 0.74 | S100A9 (0.63) | HSD11B1HSP90AA1HSP90AB1L3MBTL1ALDH1A1 | |
| SCHEMBL30926954 | 0.73 | MEN1 (0.64) | L3MBTL1ALDH1A1SMN1; SMN2LIMK1LIMK2 | |
| SCHEMBL27179907 | 0.73 | MEN1 (0.64) | L3MBTL1ALDH1A1SMN1; SMN2LIMK1LIMK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220378763-A1 | COMPOUND FOR TREATMENT OF ACUTE INFLAMMATION IN THE MYOCARDIUM | CALPROTECT AB (SE) | 2022-12-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220378763-A1 | COMPOUND FOR TREATMENT OF ACUTE INFLAMMATION IN THE MYOCARDIUM | TNNT2, TNNI3, HMGB1 | HSD11B1 1907/4885HSP90AA1 277/4885HSP90AB1 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.