Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 2/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26845915 | 1.00 | SMN1; SMN2 (0.50) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24815673 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986910 | 0.85 | SMN1; SMN2 (0.67) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986546 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24817130 | 0.83 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29986727 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24815800 | 0.74 | SMN1; SMN2 (0.49) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24814430 | 0.73 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL24815672 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2POLBALDH1A1NPC1RAB9A | |
| SCHEMBL29987155 | 0.72 | ALDH1A1 (0.46) | SMN1; SMN2POLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022251343-A2 | CDGSH IRON SULFUR DOMAIN 2 ACTIVATORS AND USE THEREOF | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2022-12-01 | — | — | WO | disclosed |