Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TNKS | O95271 | 3/20 | 0.45 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL437121 | 0.88 | TNKS (0.50) | ALDH1A1RAB9ACA1CA2MAPT | |
| SCHEMBL408245 | 0.88 | TNKS (0.50) | ALDH1A1RAB9ACA1CA2MAPT | |
| SCHEMBL29988207 | 0.85 | ALDH1A1 (0.66) | ALDH1A1ALOX15BRAB9ASMN1; SMN2SMPD1 | |
| SCHEMBL9407907 | 0.83 | ALDH1A1 (0.44) | ALDH1A1ALOX15BCA1CA2MAPT | |
| SCHEMBL407317 | 0.81 | TNKS (0.46) | ALDH1A1RAB9ACA1CA2MAPT | |
| SCHEMBL29988293 | 0.80 | RAB9A (0.41) | ALDH1A1ALOX15BRAB9ASMN1; SMN2MAPT | |
| SCHEMBL29988627 | 0.80 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTMAPK1POLB | |
| SCHEMBL439177 | 0.80 | ALDH1A1 (0.62) | ALDH1A1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL408370 | 0.80 | ALDH1A1 (0.62) | ALDH1A1RAB9ASMN1; SMN2MAPTMAPK1 | |
| SCHEMBL442998 | 0.80 | PKM (0.41) | SMN1; SMN2TP53ADCY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |