Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.37 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29988217 | 0.87 | ALDH1A1 (0.41) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL29082336 | 0.82 | ALDH1A1 (0.41) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL29082339 | 0.82 | ALDH1A1 (0.41) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL29988906 | 0.82 | MTNR1A (0.41) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL29988751 | 0.80 | ALDH1A1 (0.60) | RAB9ATP53ALDH1A1ALOX15BPOLB | |
| SCHEMBL30578684 | 0.80 | ALOX15B (0.44) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL29082684 | 0.80 | TNKS (0.46) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL30685474 | 0.80 | ALDH1A1 (0.59) | RAB9ANPC1USP2HPGDTSHR | |
| SCHEMBL30578686 | 0.78 | THRB (0.45) | RAB9ANPC1ALDH1A1ALOX15BKDM4E | |
| SCHEMBL30578697 | 0.78 | ALDH1A1 (0.41) | RAB9ANPC1USP2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212902-A1 | MODULATORS OF INTEGRATED STRESS RESPONSE PATHWAY | ALTOS LABS, INC. (US) | 2022-10-06 | — | — | WO | disclosed |