Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24656058 | 0.84 | CHEK2 (0.46) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL21531034 | 0.80 | CYP1A2 (0.57) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL29990409 | 0.80 | FPR3 (0.47) | CYP1A2ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL15228258 | 0.80 | KDM4E (0.42) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL17697619 | 0.78 | SMN1; SMN2 (0.43) | CYP1A2ALDH1A1KDM4ESMN1; SMN2HTT | |
| SCHEMBL1252013 | 0.77 | CHEK2 (0.61) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL3298763 | 0.74 | ALDH1A1 (0.56) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL26089460 | 0.74 | PKM (0.64) | CYP1A2ALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL9607575 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EHPGDLMNAGLA | |
| SCHEMBL13388126 | 0.73 | ADORA2A (0.40) | ALDH1A1KDM4ESMN1; SMN2HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334301-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | University College Cardiff Consultants Limited (GB) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022234271-A1 | HETEROARYL COMPOUNDS USEFUL IN THE TREATMENT OF COGNITIVE DISORDERS | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |