SCHEMBL2999160

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3011126	0.91	CSF1R (0.44)	CSF1RPRKCQMAP4K1CNR2
	SCHEMBL3007636	0.88	RIPK1 (0.40)	CSF1RADORA1CHEK1KCNH2NHERF1
	SCHEMBL27808374	0.88	EPHX2 (0.42)	EPHX2ADORA1CHEK1KCNH2ADORA2A
	SCHEMBL27808406	0.86	FFAR1 (0.49)	EPHX2CHEK1KCNH2NR1H4
	SCHEMBL3012538	0.85	EPHX2 (0.40)	EPHX2CHEK1KCNH2
	SCHEMBL3005194	0.84	ADORA1 (0.45)	CSF1RADORA1CHEK1KCNH2MAPT
	SCHEMBL3007638	0.83	ADORA1 (0.46)	CSF1RADORA1CHEK1KCNH2MAPT
	SCHEMBL3003645	0.82	HCAR3 (0.43)	CHEK1KCNH2CNR1CNR2
	SCHEMBL3008877	0.81	ADORA2A (0.42)	ADORA1CHEK1KCNH2MAPTADORA2A
	SCHEMBL3004392	0.80	PLAU (0.42)	CSF1RCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.