Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL234362 | 0.79 | ALOX5 (0.42) | EPHX1NAAAHTTNPC1CYP2C19 | |
| SCHEMBL14759074 | 0.78 | EPHX1 (0.41) | EPHX1NAAAHTTALDH1A1NPC1 | |
| SCHEMBL11301887 | 0.77 | EPHX1 (0.52) | EPHX1NAAAHTTMEN1KMT2A | |
| SCHEMBL237302 | 0.76 | ALOX5 (0.41) | EPHX1NAAAHTTNPC1CYP2C19 | |
| SCHEMBL14759108 | 0.76 | LMNA (0.39) | EPHX1NAAAALDH1A1KMT2ANPC1 | |
| SCHEMBL1376315 | 0.75 | LMNA (0.44) | EPHX1NAAAALDH1A1MEN1KMT2A | |
| SCHEMBL14759197 | 0.75 | EPHX1 (0.48) | EPHX1NAAAHTTALDH1A1MEN1 | |
| Bicarbonate SCHEMBL19329248 | 0.74 | EPHX1 (0.47) | EPHX1NAAAHTTALDH1A1L3MBTL1 | |
| Bicarbonate SCHEMBL7189359 | 0.74 | EPHX1 (0.47) | EPHX1NAAAHTTALDH1A1L3MBTL1 | |
| SCHEMBL1374286 | 0.73 | LMNA (0.45) | EPHX1NAAAALDH1A1SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |