Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 7/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 12/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.43 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.43 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.43 |
| ▸ | TGFBR2 | P37173 | 3/20 | 0.43 |
| ▸ | MAP3K20 | Q9NYL2 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14845042 | 1.00 | THRB (0.58) | THRBTGFBR1MAPK14MAPK13MAPK12 | |
| SCHEMBL2524801 | 0.96 | THRB (0.54) | THRBTGFBR1MAPK14MAPK13MAPK12 | |
| SCHEMBL14844930 | 0.88 | TGFBR1 (0.56) | THRBTGFBR1MAPK14TGFBR2MAP3K20 | |
| SCHEMBL14844378 | 0.85 | TGFBR1 (0.46) | THRBTGFBR1MAPK14TGFBR2MAP3K20 | |
| SCHEMBL18115014 | 0.84 | THRB (0.59) | THRBTGFBR1MAPK14TGFBR2MAP3K20 | |
| SCHEMBL24553883 | 0.83 | ADORA2A (0.42) | THRBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL25223834 | 0.83 | CSNK1D (0.55) | THRBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29683181 | 0.83 | ADORA2A (0.42) | THRBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL24553862 | 0.83 | MAPK14 (0.46) | THRBMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29682984 | 0.83 | MAPK14 (0.46) | THRBMAPK14MAPK13MAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-06-22 | — | — | US | disclosed |
| EP-4126878-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | Gritscience Biopharmaceuticals Co., Ltd. (CN) | 2023-02-08 | — | — | EP | disclosed |
| CN-115335057-A | Method for inhibiting casein kinase | 北京原基华毅生物科技有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-115298183-A | Compounds as casein kinase inhibitors | 北京原基华毅生物科技有限公司 | 2022-11-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192699-A1 | COMPOUNDS AS CASEIN KINASE INHIBITORS | CSNK2A3, CSNK1A1, CSNK1G3 | THRB 2602/4885TGFBR1 3541/4885MAPK14 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.