Pisonin C

Pisonin C

SCHEMBL29994635

COc1c(O)cc2occc(=O)c2c1O

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.56
FLT3 P36888 3/20 0.56
MEN1 O00255 3/20 0.56
NPC1 O15118 3/20 0.56
POLB P06746 3/20 0.56
KMT2A Q03164 3/20 0.56
RAB9A P51151 2/20 0.56
GFER P55789 2/20 0.56
GABRP O00591 1/20 0.56
GABRD O14764 1/20 0.56
PIM1 P11309 1/20 0.56
GABRA1 P14867 1/20 0.56
GABRB1 P18505 1/20 0.56
GABRG2 P18507 1/20 0.56
GABRB3 P28472 1/20 0.56
GABRA5 P31644 1/20 0.56
GABRA3 P34903 1/20 0.56
GABRA2 P47869 1/20 0.56
GABRB2 P47870 1/20 0.56
GABRA4 P48169 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pisonin A SCHEMBL30895182 0.86 PTGS1 (0.61) MAPTFLT3POLBMKNK2OPRD1
SCHEMBL28387796 0.80 PTPRS (0.54) MAPTMEN1POLBKMT2AGABRP
SCHEMBL29994681 0.76 EGFR (0.67) MAPTFLT3MEN1NPC1POLB
SCHEMBL27986015 0.76 PTGS1 (0.59) MAPTFLT3MEN1NPC1KMT2A
SCHEMBL17237767 0.76 ABCB1 (0.53) MAPTMEN1NPC1KMT2AKDM4E
Pisonin B SCHEMBL30587309 0.75 PTGS1 (0.76) MAPTFLT3MEN1NPC1POLB
Hispidulin SCHEMBL514926 0.72 POLB (1.00) MAPTFLT3MEN1NPC1POLB
Oroxylin A SCHEMBL30452350 0.72 CREB1 (1.00) MAPTFLT3MEN1NPC1POLB
Hispidulin SCHEMBL29458970 0.72 POLB (1.00) MAPTFLT3MEN1NPC1POLB
Oroxylin A SCHEMBL431423 0.72 CREB1 (1.00) MAPTFLT3MEN1NPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250334574-A1 Autoantibody Biomarkers of Ro/SS-A Antibody Negative Sjogren's Syndrome/Sjogren's Disease OKLAHOMA MED RES FOUND (US) 2025-10-30 US disclosed
CN-115197190-A Novel plant flavone derivative and preparation method and application thereof 中国海洋大学 2022-10-18 CN disclosed