Oroxylin A

Oroxylin A

SCHEMBL431423

COc1c(O)cc2oc(-c3ccccc3)cc(=O)c2c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CREB1 P16220 6/20 1.00
▸ FLT3 P36888 3/20 1.00
▸ PRSS1 P07477 2/20 1.00
▸ PRSS2 P07478 2/20 1.00
▸ PRSS3 P35030 2/20 1.00
▸ SLCO2B1 O94956 1/20 1.00
▸ PTPRS Q13332 2/20 0.95
▸ MAPT P10636 5/20 0.81
▸ MEN1 O00255 4/20 0.81
▸ KMT2A Q03164 4/20 0.81
▸ NPC1 O15118 4/20 0.81
▸ POLB P06746 3/20 0.81
▸ GABRP O00591 3/20 0.81
▸ GABRD O14764 3/20 0.81
▸ GABRA1 P14867 3/20 0.81
▸ GABRB1 P18505 3/20 0.81
▸ GABRG2 P18507 3/20 0.81
▸ GABRB3 P28472 3/20 0.81
▸ GABRA5 P31644 3/20 0.81
▸ GABRA3 P34903 3/20 0.81

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oroxylin A SCHEMBL30452350 1.00 CREB1 (1.00) CREB1FLT3PRSS1PRSS2PRSS3
SCHEMBL8064245 0.91 CREB1 (0.83) CREB1FLT3PRSS1PRSS2PRSS3
SCHEMBL17663637 0.90 CREB1 (0.81) CREB1FLT3PRSS1PRSS2PRSS3
Hispidulin SCHEMBL514926 0.90 POLB (1.00) CREB1FLT3PRSS1PRSS2PRSS3
Hispidulin SCHEMBL29458970 0.90 POLB (1.00) CREB1FLT3PRSS1PRSS2PRSS3
Mosloflavone SCHEMBL971985 0.88 KDM4E (0.81) CREB1FLT3PRSS1PRSS2PRSS3
SCHEMBL12978376 0.88 CREB1 (0.79) CREB1FLT3PRSS1PRSS2PRSS3
Mosloflavone SCHEMBL29477310 0.88 KDM4E (0.81) CREB1FLT3PRSS1PRSS2PRSS3
Pectolinarigenin SCHEMBL243686 0.88 MAPT (1.00) CREB1FLT3PRSS1PRSS2PRSS3
Pectolinarigenin SCHEMBL29606971 0.88 MAPT (1.00) CREB1FLT3PRSS1PRSS2PRSS3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1601 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122084804-A Method for detecting contents of multi-index components of cough syrup oral liquid — 2026-05-26 — — CN claimed
CN-122075558-A Application of semen oroxyli total flavonoids in preparing medicament for treating uveitis — 2026-05-26 — — CN claimed
WO-2026107262-A1 PROLONGED, SCAFFOLD-MEDIATED DELIVERY OF ANGIOGENIC COMPOUNDS EFEMORAL MEDICAL, INC. (US) 2026-05-21 — — WO claimed
CN-122056935-A Application of semen oroxyli total flavone in preparing medicament for treating atopic dermatitis 南方医科大学 2026-05-19 — — CN claimed
US-20260108451-A1 COMPOSITIONS FOR THE MANAGEMENT OF HIRSUTISM MAJEED ANJU (IN) 2026-04-23 — — US claimed
EP-4714440-A2 A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS Kurek, Janusz (PL) 2026-03-25 — — EP claimed
CN-121583384-A Nucleic acid-small molecule non-covalent complex and preparation method and application thereof 上海中医药大学 2026-02-27 — — CN claimed
EP-4684792-A1 ANTIMICROBIAL AGENT AND USE THEREOF Herzog, Artur (CH) 2026-01-28 — — EP claimed
EP-4683527-A1 VAPORIZABLE ALKALOID COMPOSITIONS AND METHODS OF USE THEREOF Ready Mix Naturals, LLC (US) 2026-01-28 — — EP claimed
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof Ready Mix Naturals, LLC (US) 2025-12-16 — — US claimed
EP-1254131-A4 EXTRACTION OF FLAVONOIDS BIOREX HEALTH LTD (AU) 2003-04-23 — — EP claimed
CN-1404831-A Use of Radix scutellariae glycoside in preparing medicine for treating prostatic disorders and its medicinal composition CHINESE MEDICINE UNIV (CN) 2003-03-26 — — CN claimed
WO-2003015737-A1 USE OF OROXYLIN A FOR THE PRODUCTION OF COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE PROPHYLAXIS AND TREATMENT OF INFLAMMATORY SKIN CONDITIONS AND/OR FOR SKIN PROTECTION OF DETERMINATE SENSITIVE AND DRY SKIN BEIERSDORF AG (DE) 2003-02-27 — — WO claimed
CN-1395573-A Extraction of flavonoids BIOREX HEALTH LTD (AU) 2003-02-05 — — CN claimed
EP-1254131-A1 EXTRACTION OF FLAVONOIDS Biorex Health Limited (AU) 2002-11-06 — — EP claimed
WO-2001051482-A1 EXTRACTION OF FLAVONOIDS BIOREX HEALTH LIMITED (AU) 2001-07-19 — — WO claimed
EP-0332478-B1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECH (FR) 1992-03-25 — — EP claimed
CN-1037834-A With hydration lamellar fat mutually or liposome is the compositions of main component, wherein contain the Radix Scutellariae extract or contain wherein a kind of component at least, and cosmetics or medicament, especially skin is had antiallergic, the compositions of antiinflammatory or defying age performance LVMH RECH (FR) 1989-12-13 — — CN claimed
WO-1989008447-A1 LIPOSOMES CONTAINING SCUTELLARIA EXTRACTS LVMH RECHERCHE (FR) 1989-09-21 — — WO claimed
EP-0332478-A1 Liposomes containing Scutellaria extracts LVMH RECHERCHE (FR) 1989-09-13 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108451-A1 COMPOSITIONS FOR THE MANAGEMENT OF HIRSUTISM CYP17A1, SRD5A2, SRD5A1 CREB1 2062/4885FLT3 1913/4885PRSS1 2698/4885
US-12497381-B2 Vaporizable alkaloid compositions and methods of use thereof CHRM5, NNMT, CHRM1 CREB1 2410/4885FLT3 1002/4885PRSS1 3661/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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