Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 6/20 | 1.00 |
| ▸ | FLT3 | P36888 | 3/20 | 1.00 |
| ▸ | PRSS1 | P07477 | 2/20 | 1.00 |
| ▸ | PRSS2 | P07478 | 2/20 | 1.00 |
| ▸ | PRSS3 | P35030 | 2/20 | 1.00 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 1.00 |
| ▸ | PTPRS | Q13332 | 2/20 | 0.95 |
| ▸ | MAPT | P10636 | 5/20 | 0.81 |
| ▸ | MEN1 | O00255 | 4/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.81 |
| ▸ | NPC1 | O15118 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 3/20 | 0.81 |
| ▸ | GABRP | O00591 | 3/20 | 0.81 |
| ▸ | GABRD | O14764 | 3/20 | 0.81 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.81 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.81 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.81 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.81 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.81 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oroxylin A SCHEMBL431423 | 1.00 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL8064245 | 0.91 | CREB1 (0.83) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL17663637 | 0.90 | CREB1 (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Hispidulin SCHEMBL29458970 | 0.90 | POLB (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Hispidulin SCHEMBL514926 | 0.90 | POLB (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL12978376 | 0.88 | CREB1 (0.79) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Mosloflavone SCHEMBL971985 | 0.88 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Mosloflavone SCHEMBL29477310 | 0.88 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Pectolinarigenin SCHEMBL243686 | 0.88 | MAPT (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Pectolinarigenin SCHEMBL29606971 | 0.88 | MAPT (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117771215-A | Drug delivery system for targeted treatment of osteoporosis and preparation method thereof | 上海大学 | 2024-03-29 | — | — | CN | disclosed |
| CN-117645594-A | Preparation method of oroxylin A | 南京杰运医药科技有限公司 | 2024-03-05 | — | — | CN | disclosed |
| US-20230355726-A1 | FIBRINOLYTIC ENZYME COMPOSITION FOR FIBROSIS TREATMENT | ADVANCED ENZYME TECHNOLOGIES LTD. (IN) | 2023-11-09 | — | — | US | disclosed |
| CN-116870050-A | Application of moldavica dragonhead in preparation of lipid metabolism regulating drugs | 内蒙古科技大学包头医学院 | 2023-10-13 | — | — | CN | disclosed |
| CN-111920800-B | Application of oroxylin A in treating osteoporosis and promoting fracture healing | 中国人民解放军海军军医大学第一附属医院 | 2023-06-13 | — | — | CN | disclosed |