SCHEMBL275071

SCHEMBL275071

CC(=CCC(=O)O)C(=O)O

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.43
CYP2D6 P10635 1/20 0.43
ALOX15 P16050 1/20 0.43
PTGS1 P23219 1/20 0.34
AKR1C3 P42330 1/20 0.34
CD81 P60033 1/20 0.34
FFAR3 O14843 2/20 0.33
LMNA P02545 1/20 0.33
SLC15A2 Q16348 1/20 0.33
GRIK2 Q13002 1/20 0.33
TSHR P16473 1/20 0.33
NR1H3 Q13133 1/20 0.33
TRPA1 O75762 1/20 0.32
LCK P06239 1/20 0.32
FYN P06241 1/20 0.32
CYP2C9 P11712 1/20 0.31
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7138870 1.00 ALDH1A1 (0.43) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL2727259 1.00 ALDH1A1 (0.43) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL1622643 0.97 ALDH1A1 (0.41) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL1621314 0.97 ALDH1A1 (0.41) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL1623651 0.97 ALDH1A1 (0.41) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
Methacrylic Acid SCHEMBL30704265 0.91 ALOX15 (0.36) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL11024924 0.88 ALDH1A1 (0.47) ALDH1A1CYP2D6ALOX15FFAR3LMNA
SCHEMBL474842 0.83 TRPA1 (0.38) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
SCHEMBL474840 0.83 TRPA1 (0.38) ALDH1A1CYP2D6ALOX15PTGS1AKR1C3
Acetone SCHEMBL5520081 0.81 TRPA1 (0.36) ALDH1A1PTGS1AKR1C3CD81FFAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 411 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025059302-A1 COMPOSITIONS AND METHODS OF USE THEREOF FOR TREATMENT AND MODULATION OF ACUTE AND CHRONIC SYMPTOMS OF MITOCHONDRIAL DISEASE AND DYSFUNCTION THE CHILDREN'S HOSPITAL OF PHILADELPHIA (US) 2025-03-20 WO claimed
US-20250057153-A1 Maleated Natural Oil Derivatives As Agrochemical Inert Ingredients INDORAMA VENTURES OXIDES LLC 2025-02-20 US claimed
US-12171731-B2 Methods and compositions for the treatment of steatosis-associated disorders DUKE UNIVERSITY (US) 2024-12-24 US claimed
EP-4062913-B1 SOLID ORAL FORMULATION OF UTIDELONE BEIJING BIOSTAR PHARMACEUTICALS CO LTD (CN) 2024-05-08 EP claimed
US-20230285329-A1 Methods and Compositions for the Treatment of Steatosis-Associated Disorders DUKE UNIVERSITY (US) 2023-09-14 US claimed
US-20230285328-A1 Methods and Compositions for the Treatment of Steatosis-Associated Disorders DUKE UNIVERSITY (US) 2023-09-14 US claimed
CN-116355373-A Polylactic acid-based composite material and preparation method thereof 四川大学 2023-06-30 CN claimed
WO-2022190030-A1 A TOPICAL FORMULATION FOR THE TREATMENT OF SKIN DISEASES AVACA PHARMA PRIVATE LIMITED (IN) 2022-09-15 WO claimed
CN-106592242-B Modified epoxy resin large tow universal carbon fiber sizing agent, preparation method and application thereof 中国石油化工股份有限公司 2020-11-06 CN claimed
CN-106592236-B Small tow universal carbon fiber sizing agent, preparation method and application thereof 中国石油化工股份有限公司 2020-09-04 CN claimed
US-20070048337-A1 Aldol-crosslinked polymeric hydrogel adhesives ACTAMAX SURGICAL MATERIALS, LLC 2007-03-01 US claimed
US-20070048251-A1 Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive ACTAMAX SURGICAL MATERIALS, LLC 2007-03-01 US claimed
WO-2006125976-A1 AN EMBEDMENT CASTING COMPOSITION LUCITE INTERNATIONAL UK LIMITED (GB) 2006-11-30 WO claimed
EP-0969793-A1 FOIL FOR WRAPPING HAIR ENDS Wella Aktiengesellschaft (DE) 2000-01-12 EP claimed
WO-1999029282-A1 FOIL FOR WRAPPING HAIR ENDS WELLA AKTIENGESELLSCHAFT (DE) 1999-06-17 WO claimed
US-4777114-A AQUEOUS EMULSION OF FILM FORMING RESIN PROTECTIVE COLLOID CONTAINING PHOTOSENSITIVE AND HYDROPHOBIC SEGMENTS AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1988-10-11 US claimed
US-4684554-A HEAT SEALABLE SEALS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1987-08-04 US claimed
EP-0045968-B1 FILLED THERMOPLASTIC COMPOSITIONS BASED ON ETHYLENE INTERPOLYMERS AND POLYESTER, POLYETHER AND POLYETHER ESTER PLASTICIZERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-07-17 EP claimed
US-4480061-A Wood-like articles made from cellulosic filler loaded ethylene interpolymers E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-30 US claimed
US-4461809-A GRAFT POLYMER OF ETHYLENE, PROPYLENE, AND ALKYL ESTER OF OLEFINIC DICARBOXYLIC ACID MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1984-07-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250057153-A1 Maleated Natural Oil Derivatives As Agrochemical Inert Ingredients MSL1, MGLL, NOTUM ALDH1A1 2815/4885CYP2D6 2524/4885ALOX15 77/4885
US-20070048337-A1 Aldol-crosslinked polymeric hydrogel adhesives ALDOA, ADSL, ALDH1A2 ALDH1A1 9/4885CYP2D6 2481/4885ALOX15 491/4885
US-20070048251-A1 Methods for sealing an orifice in tissue using an aldol-crosslinked polymeric hydrogel adhesive SI, ADSL, AOX1 ALDH1A1 27/4885CYP2D6 2371/4885ALOX15 218/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.