Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 5/20 | 0.50 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MMP9 | P14780 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.48 |
| ▸ | PGR | P06401 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23014458 | 0.90 | TP53 (0.46) | CNR2MMP1MMP13ADAM17MAPT | |
| SCHEMBL23014638 | 0.85 | L3MBTL1 (0.50) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL23014637 | 0.84 | KEAP1 (0.62) | MAPTALDH1A1TP53POLBTHRB | |
| SCHEMBL23014633 | 0.83 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL23014087 | 0.83 | GAA (0.44) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL23014627 | 0.82 | ALDH1A1 (0.47) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL23014191 | 0.82 | ALDH1A1 (0.44) | MAPTLMNAALDH1A1NPSR1MEN1 | |
| SCHEMBL23014077 | 0.82 | KEAP1 (0.49) | MAPTALDH1A1MEN1KMT2ATP53 | |
| SCHEMBL23014634 | 0.81 | ALDH1A1 (0.46) | CNR2MAPTLMNAALDH1A1NPSR1 | |
| SCHEMBL23014067 | 0.81 | KEAP1 (0.46) | MAPTALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2022-09-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220305121-A1 | N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT | TLR1, TLR3, TLR2 | CNR2 615/4885MMP1 4856/4885MMP13 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.