Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GHSR | Q92847 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8249064 | 0.83 | DRD2 (0.47) | DRD2SLC6A4HTR2AHTR7HTR6 | |
| SCHEMBL13180387 | 0.82 | MAPT (0.44) | MAPTTDP1LMNADRD2SLC6A4 | |
| SCHEMBL462156 | 0.78 | FAAH (0.56) | MAPTFAAHMGLLLMNAKDM4E | |
| SCHEMBL27445742 | 0.77 | ESR1 (0.36) | MAPTTDP1FAAHMGLLDRD2 | |
| SCHEMBL9688702 | 0.76 | MAPT (0.41) | MAPTTDP1LMNADRD2SLC6A4 | |
| Hydrochloric Acid SCHEMBL30268833 | 0.75 | FAAH (0.57) | MAPTFAAHMGLLLMNAKDM4E | |
| SCHEMBL27440206 | 0.74 | KMO (0.33) | FAAHMGLLGCGR | |
| SCHEMBL27439688 | 0.73 | KMO (0.33) | FAAHMGLLGCGR | |
| SCHEMBL11012597 | 0.73 | DRD2 (0.57) | DRD2SLC6A4HTR2AHTR7HTR6 | |
| SCHEMBL6324800 | 0.73 | DRD2 (0.46) | DRD2HTR2AHTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022199662-A1 | POLYCYCLIC COMPOUND AND APPLICATION THEREOF | 四川汇宇制药股份有限公司 | 2022-09-29 | — | — | WO | disclosed |