Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | SCD | O00767 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2774476 | 0.86 | ACHE (0.42) | HTR3AACHEDRD2SLC6A4 | |
| SCHEMBL13180387 | 0.82 | MAPT (0.44) | MAPTTDP1LMNAHTR3ASCD | |
| SCHEMBL23218521 | 0.80 | MAPT (0.41) | MAPTLMNAACHECA12CA1 | |
| SCHEMBL29591789 | 0.80 | MAPT (0.41) | MAPTLMNAACHECA12CA1 | |
| SCHEMBL9689456 | 0.79 | MAPT (0.62) | MAPTTDP1LMNAACHETP53 | |
| SCHEMBL8276503 | 0.79 | FAAH (0.42) | MAPTLMNAHTR3ATP53 | |
| SCHEMBL9512394 | 0.77 | MAPT (0.68) | MAPTTDP1LMNATP53 | |
| SCHEMBL7307801 | 0.77 | LMNA (0.62) | MAPTTDP1LMNAHTR3ANQO1 | |
| SCHEMBL2615284 | 0.76 | LMNA (0.45) | MAPTTDP1LMNAHTR3ACA12 | |
| SCHEMBL7315256 | 0.76 | LMNA (0.45) | MAPTTDP1LMNAHTR3ANQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109574945-B | Isoxazoline derivatives and their use in agriculture | 东莞市东阳光农药研发有限公司 | 2021-04-20 | — | — | CN | disclosed |
| EP-0298921-B1 | 1,2-BENZISOXAZOLES AND 1,2-BENZISOTHIAZOLES | CIBA-GEIGY AG (CH) | 1992-12-23 | — | — | EP | disclosed |
| US-4859691-A | Certain 1,2-benzisoxazole derivatives | CIBA-GEIGY CORPORATION (US) | 1989-08-22 | — | — | US | disclosed |
| EP-0298921-A1 | 1,2-Benzisoxazoles and 1,2-benzisothiazoles | CIBA-GEIGY AG (CH) | 1989-01-11 | — | — | EP | disclosed |