SCHEMBL300000

SCHEMBL300000

C=CC(=O)OCC=COc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.55
TGM2 P21980 1/20 0.40
CYP3A4 P08684 2/20 0.38
SMN1; SMN2 Q16637 3/20 0.35
GAA P10253 2/20 0.35
GLA P06280 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 1/20 0.35
ALDH1A1 P00352 5/20 0.35
TSHR P16473 6/20 0.35
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
AKT1 P31749 1/20 0.35
ALOX15 P16050 1/20 0.34
KDM4E B2RXH2 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
LTA4H P09960 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16518521 0.87 THRB (0.41) THRBTGM2CYP3A4SMN1; SMN2ALDH1A1
SCHEMBL16518462 0.87 THRB (0.41) THRBTGM2CYP3A4SMN1; SMN2ALDH1A1
SCHEMBL8821190 0.84 THRB (0.45) THRBTGM2CYP3A4SMN1; SMN2GAA
SCHEMBL19560250 0.81 THRB (0.36) THRBTGM2CYP3A4ALDH1A1TSHR
SCHEMBL1479357 0.80 ALDH1A1 (0.46) THRBSMN1; SMN2RAB9AALDH1A1TSHR
SCHEMBL299827 0.78 ELANE (0.41) THRBCYP3A4HTTRAB9AALDH1A1
SCHEMBL890323 0.78 THRB (0.45) THRBCYP3A4GAARAB9AALDH1A1
SCHEMBL16518569 0.78 THRB (0.49) THRBCYP3A4HTTALDH1A1TSHR
SCHEMBL891181 0.77 MMP1 (0.51) THRBSMN1; SMN2GAAALDH1A1KDM4E
SCHEMBL137828 0.77 MMP1 (0.51) THRBSMN1; SMN2GAAALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 206 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111417662-B Chemically resistant polyacrylates and pressure-sensitive adhesives based thereon 德莎欧洲股份公司 2023-02-03 CN claimed
EP-3235852-A1 PHOTOACTIVE POLYMER MATERIALS Rolic AG (CH) 2017-10-25 EP claimed
EP-2655478-B1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2017-06-14 EP claimed
EP-2655478-A1 PHOTOACTIVE POLYMER MATERIALS Rolic AG (CH) 2013-10-30 EP claimed
US-20130281564-A1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2013-10-24 US claimed
US-8500807-B2 Photochromic intraocular lens CARL ZEISS MEDITEC SAS (FR) 2013-08-06 US claimed
WO-2012085048-A1 PHOTOACTIVE POLYMER MATERIALS ROLIC AG (CH) 2012-06-28 WO claimed
EP-1834195-B9 PHOTOCHROMIC INTRAOCULAR LENS IOLTECHNOLOGIE PRODUCTION (FR) 2010-07-21 EP claimed
EP-1834195-B1 PHOTOCHROMIC INTRAOCULAR LENS IOLTECHNOLOGIE PRODUCTION (FR) 2010-03-17 EP claimed
WO-2009133011-A1 BENZOXAZINE COMPOSITIONS CONTAINING (CO)POLYMER HENKEL AG & CO. KGAA (DE) 2009-11-05 WO claimed
EP-0324480-B1 Photopolymerizable compositions and elements for refractive index imaging DU PONT (US) 1994-04-13 EP claimed
EP-0324481-B1 STORAGE STABLE PHOTOPOLYMERIZABLE COMPOSITION FOR REFRACTIVE INDEX IMAGING E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-05-05 EP claimed
EP-0324482-B1 PROCESS OF FORMING REFLECTION HOLOGRAMS IN PHOTOPOLYMERIZABLE LAYERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-31 EP claimed
US-5198303-A Paintable high specific adhesion polyvinyl halide copolymer compositions THE B. F. GOODRICH COMPANY (US) 1993-03-30 US claimed
US-5098803-A Photopolymerization of a composition for holographic multilayer element E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-03-24 US claimed
US-4994347-A Polymeric binder, n-vinyl carbazole and photoinitiator system E. I. DU PONT DE NEMOURS AND COMPANY (US) 1991-02-19 US claimed
EP-0324481-A2 Storage stable photopolymerizable composition for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
EP-0324482-A2 Process of forming reflection holograms in photopolymerizable layers E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
EP-0324480-A2 Photopolymerizable compositions and elements for refractive index imaging E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-19 EP claimed
US-4133942-A Polymeric carrier for a controlled synthesis of peptides and the method of its preparation CESKOSLOVENSKA AKADEMIE VED (CS) 1979-01-09 US claimed