Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30001951

N[C@H](CO)C[C@@H]1CCNC1=O.O=C(O)C(F)(F)F

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24754822 0.88 CTSL (0.32) CTSLCTSB
SCHEMBL24754817 0.88 CTSL (0.32) CTSLCTSB
SCHEMBL23866547 0.88 CTSL (0.32) CTSLCTSB
Hydrochloric Acid SCHEMBL30002377 0.86 CTSL (0.32) CTSLCTSB
Hydrochloric Acid SCHEMBL31374949 0.86 CTSL (0.32) CTSLCTSB
Trifluoroacetic Acid SCHEMBL25276894 0.82
Trifluoroacetic Acid SCHEMBL29047477 0.82 CTSV (0.39)
Trifluoroacetic Acid SCHEMBL30489485 0.82
Trifluoroacetic Acid SCHEMBL29943453 0.82 CTSV (0.39)
SCHEMBL24785729 0.80 L3MBTL1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250122153-A1 Protease Inhibitors as Antivirals ACEA Therapeutics, Inc. (US) 2025-04-17 US disclosed
US-11987554-B2 Protease inhibitors as antivirals VIVASOR, INC. (US) 2024-05-21 US disclosed
EP-4347034-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2024-04-10 EP disclosed
CN-117769541-A protease inhibitors as antiviral agents 艾森医药有限公司 2024-03-26 CN disclosed
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2023-10-12 US disclosed
US-11753373-B2 Protease inhibitors as antivirals ACEA Therapeutics, Inc. (US) 2023-09-12 US disclosed
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. 2023-01-26 US disclosed
WO-2022256434-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACEA Therapeutics, Inc. (US) 2022-12-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122153-A1 Protease Inhibitors as Antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-20230026438-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-11753373-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-11987554-B2 Protease inhibitors as antivirals ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885
US-20230322668-A1 PROTEASE INHIBITORS AS ANTIVIRALS ACE, ACE2, TMPRSS15 CTSL 4/4885CTSB 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.