Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | BCL2 | P10415 | 2/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 10/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 9/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 8/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 8/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22163625 | 0.91 | PSMB1 (0.58) | BCL2PSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL30002299 | 0.90 | CTSS (0.54) | BCL2PSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL30604544 | 0.90 | CTSS (0.54) | BCL2PSMB1PSMB5PSMB9PSMB8 | |
| SCHEMBL29152266 | 0.89 | CTSL (0.56) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL30001953 | 0.89 | CTSL (0.56) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL30001520 | 0.83 | NPC1 (0.53) | NPC1RAB9A | |
| SCHEMBL30002878 | 0.83 | NPC1 (0.53) | NPC1RAB9A | |
| SCHEMBL30002718 | 0.83 | CTSS (0.56) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL30604541 | 0.83 | CTSS (0.56) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL20111123 | 0.83 | CTSS (0.62) | GAACTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117677382-A | Benzyloxy benzylamino amino acid derivatives that modulate TSLP/TSLPR signaling | 阿米蒂比奥有限公司 | 2024-03-08 | — | — | CN | disclosed |
| CN-110325509-B | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-116836083-A | Functional derivative compounds of alanine and proline amino acids and pharmaceutical compositions containing the same | 阿米蒂比奥有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | disclosed |