Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAOB | P27338 | 3/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30001520 | 1.00 | NPC1 (0.53) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL30002267 | 0.88 | GID4 (0.59) | NPC1RAB9AMAOBMAOASMN1; SMN2 | |
| SCHEMBL30002836 | 0.88 | GID4 (0.59) | NPC1RAB9AMAOBMAOASMN1; SMN2 | |
| SCHEMBL31441380 | 0.85 | MME (0.54) | MAOBFFAR1PPARAADAMTS5MMP2 | |
| SCHEMBL30002279 | 0.83 | GAA (0.52) | NPC1RAB9A | |
| SCHEMBL21696783 | 0.78 | ALDH1A1 (0.52) | NPC1RAB9ASMN1; SMN2ALDH1A1MEN1 | |
| SCHEMBL9518560 | 0.76 | NPC1 (0.53) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL7395329 | 0.76 | NPC1 (0.53) | NPC1RAB9AMAOBMAOANR4A2 | |
| SCHEMBL30002045 | 0.74 | MME (0.53) | MAOBFFAR1PPARAADAMTS5MMP2 | |
| SCHEMBL8433399 | 0.74 | NPC1 (0.57) | NPC1RAB9AMAOBMAOANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255801-A1 | BENZYLOXY-BENZYLAMINYL AMINO ACID DERIVATIVE FOR ADJUSTING TSLP/TSLPR SIGNAL TRANSMISSION | (주)앰틱스바이오 | 2022-12-08 | — | — | WO | disclosed |