Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.68 |
| ▸ | ADRB1 | P08588 | 12/20 | 0.68 |
| ▸ | ADRB3 | P13945 | 12/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL29142960 | 0.98 | ADRB2 (0.66) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL9463879 | 0.92 | ADRB2 (0.73) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL120454 | 0.88 | ALDH1A1 (0.61) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL27601183 | 0.83 | ALDH1A1 (0.51) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL446204 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL17629572 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL120453 | 0.82 | ALDH1A1 (0.56) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL9106286 | 0.82 | ALDH1A1 (0.54) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL17629569 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3TSHRALDH1A1 | |
| SCHEMBL29613210 | 0.82 | ADRB2 (0.63) | ADRB2ADRB1ADRB3TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901287-A | Treatment of emesis and nausea with minimal dose of olanzapine | 斯塔顿治疗公司 | 2022-08-12 | — | — | CN | claimed |