Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28892725 | 1.00 | ALDH1A1 (0.36) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL30003319 | 0.84 | GAA (0.40) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL28892714 | 0.84 | GAA (0.40) | ALDH1A1MAPTKDM4EGAAPKM | |
| SCHEMBL30003289 | 0.83 | GAA (0.35) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL28892418 | 0.81 | KIT (0.37) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL30003338 | 0.81 | KIT (0.37) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL28892558 | 0.81 | LMNA (0.38) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL30002409 | 0.81 | LMNA (0.38) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL28892412 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL30003416 | 0.81 | KMT2A (0.50) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-B | Nitrogen-containing condensed ring derivative, pharmaceutical composition, and preparation method and application thereof | 长春金赛药业有限责任公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |