Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.50 |
| ▸ | PTPRC | P08575 | 1/20 | 0.50 |
| ▸ | PTPRF | P10586 | 1/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.50 |
| ▸ | PTPA | Q15257 | 1/20 | 0.50 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29072069 | 0.89 | LMNA (0.51) | LMNAPTPN1PTPRCPTPRFPTPN2 | |
| SCHEMBL28892328 | 0.84 | MAPT (0.52) | LMNAMAPTALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL28892555 | 0.78 | POLB (0.51) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12894813 | 0.78 | ALDH1A1 (0.80) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10760954 | 0.77 | MAPT (0.60) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL7472861 | 0.77 | TSHR (0.67) | LMNAALDH1A1SMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL28892519 | 0.76 | POLB (0.49) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10530351 | 0.74 | MEN1 (0.46) | LMNAPTPN1PTPRCPTPRFPTPN2 | |
| SCHEMBL7139983 | 0.74 | SMN1; SMN2 (0.72) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL30216371 | 0.73 | ILK (0.66) | LMNAMAPTALDH1A1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232144-A | Nitrogen-containing fused ring derivative, pharmaceutical composition, preparation method and application thereof | 长春金赛药业有限责任公司 | 2022-10-25 | — | — | CN | disclosed |