Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 4/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895686 | 0.77 | NPC1 (0.45) | BRD4 | |
| SCHEMBL28425898 | 0.77 | BRD4 (0.46) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| SCHEMBL16393627 | 0.77 | BRD4 (0.51) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| Hydrogen Sulfide SCHEMBL27539552 | 0.75 | BRD4 (0.50) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| Ammonia Solution, Strong SCHEMBL27714733 | 0.75 | BRD4 (0.50) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| SCHEMBL23583810 | 0.75 | ADRA2A (0.34) | ADRA2ACTSKSLC6A2 | |
| SCHEMBL10789751 | 0.74 | PTGS2 (0.60) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| SCHEMBL29433489 | 0.74 | PTGS2 (0.60) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| SCHEMBL28228917 | 0.74 | PTGS2 (0.56) | BRD4ADRA2AADRA1DADRA1APTGS2 | |
| SCHEMBL30407966 | 0.72 | PTGS2 (0.63) | BRD4ADRA2AADRA1DADRA1APTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087836-A1 | PROCESSES FOR PREPARING TRIAZOLE GLYCOLATE OXIDASE INHIBITORS | Cantero Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |