SCHEMBL3000297

SCHEMBL3000297

C1=Cc2ccccc2C(c2ccccc2)C1

nearest known ligand 0.42

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
KMT2A Q03164 1/20 0.38
SIGMAR1 Q99720 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29690123 1.00 MEN1 (0.38) MEN1CYP3A4CYP2D6KMT2ASIGMAR1
SCHEMBL28261353 0.85 HTR6 (0.41) MEN1KMT2A
SCHEMBL13979443 0.85 HTR2A (0.39) MEN1KMT2A
SCHEMBL28261355 0.81 DDB1 (0.39) MEN1CYP3A4CYP2D6KMT2A
SCHEMBL31122360 0.81 HTR2A (0.44) MEN1KMT2A
SCHEMBL31122364 0.81 HTR2A (0.44) MEN1KMT2A
SCHEMBL24055884 0.81 ALDH1A1 (0.33)
SCHEMBL29639145 0.80 SLC6A2 (0.45)
SCHEMBL4430948 0.79 MEN1 (0.40) MEN1CYP3A4CYP2D6KMT2ASIGMAR1
SCHEMBL22812897 0.79 DRD1 (0.40) MEN1CYP3A4CYP2D6KMT2ASIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040247698-A1 Erectile Dysfunction Treatment VALENZUELA CORTES CARMEN MARIA (CL) 2004-12-09 US claimed
CN-113200998-B Organic luminescent material and application thereof 武汉市晟承宇科技有限公司 2023-07-11 CN disclosed
CN-113173934-B Organic compound, application thereof and organic electroluminescent device 武汉市晟承宇科技有限公司 2023-05-19 CN disclosed
CN-113004261-B Compound containing multi-heterocyclic structure and application thereof 北京云基科技股份有限公司 2023-02-17 CN disclosed
CN-111909171-B Electron transport material and application thereof 北京燕化集联光电技术有限公司 2022-12-09 CN disclosed
CN-112778312-B Organic material containing indoloquinazolinedione heterocyclic structure and application thereof 北京燕化集联光电技术有限公司 2022-12-02 CN disclosed
CN-114628466-A Display device 三星显示有限公司 2022-06-14 CN disclosed
CN-114380807-A Light-emitting element and amine compound for light-emitting element 三星显示有限公司 2022-04-22 CN disclosed
CN-111662309-B Compound with multi-heterocyclic structure and application thereof 北京燕化集联光电技术有限公司 2021-11-09 CN disclosed
CN-111662309-A Compound with multi-heterocyclic structure and application thereof 北京燕化集联光电技术有限公司 2020-09-15 CN disclosed
US-8230986-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-31 US disclosed
US-8220609-B2 Torque limiter JTEKT CORPORATION (JP) 2012-07-17 US disclosed
US-20100184519-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2010-07-22 US disclosed
US-20090173591-A1 TORQUE LIMITER JTEKT CORPORATION (JP) 2009-07-09 US disclosed
EP-2009304-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-31 EP disclosed
EP-2003353-A1 TORQUE LIMITER JTEKT Corporation (JP) 2008-12-17 EP disclosed
US-20070123491-A1 Podophyllotoxin derivatives as igf-1r inhibitors BIOVITRUM AB (SE) 2007-05-31 US disclosed
EP-1615932-A2 PODOPHHYLLOTOXIN DERIVATIVES AS IGF-1R INHIBITORS Biovitrum AB (SE) 2006-01-18 EP disclosed
US-20040247698-A1 Erectile Dysfunction Treatment VALENZUELA CORTES CARMEN MARIA (CL) 2004-12-09 US disclosed
WO-2004093781-A2 PODOPHYLLOTOXIN DERIVATIVES AS IGF-1R INHIBITORS BIOVITRUM AB (SE) 2004-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040247698-A1 Erectile Dysfunction Treatment PDE3A, PDE3B, PDE12 MEN1 3117/4885CYP3A4 417/4885CYP2D6 1067/4885
US-20070123491-A1 Podophyllotoxin derivatives as igf-1r inhibitors IGF1R, IGFBP1, INSR MEN1 382/4885CYP3A4 4629/4885CYP2D6 4524/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.