Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.73 |
| ▸ | MAOB | P27338 | 1/20 | 0.73 |
| ▸ | ELANE | P08246 | 1/20 | 0.59 |
| ▸ | ALKBH3 | Q96Q83 | 2/20 | 0.47 |
| ▸ | NQO1 | P15559 | 3/20 | 0.45 |
| ▸ | POR | P16435 | 3/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.41 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9643596 | 0.90 | MAOA (0.68) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL30002985 | 0.90 | MAOA (0.68) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL30905230 | 0.85 | MAOA (1.00) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL571353 | 0.85 | MAOA (1.00) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL9627793 | 0.84 | S100A4 (0.59) | MAOAMAOBELANEMEN1NPC1 | |
| SCHEMBL7812020 | 0.81 | TDP2 (0.60) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL7812173 | 0.81 | TDP2 (0.60) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL30003080 | 0.81 | TDP2 (0.60) | MAOAMAOBELANEALKBH3NQO1 | |
| SCHEMBL8160523 | 0.81 | S100A4 (0.55) | MAOAMAOBELANELCKNPC1 | |
| SCHEMBL8161461 | 0.81 | S100A4 (0.55) | MAOAMAOBELANELCKNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5155132-A | Nonsteroidal antiinflammatory agents; treating psoriasis | SYNTEX (U.S.A.) INC. (US) | 1992-10-13 | — | — | US | disclosed |
| US-5134161-A | Enzyme inhibitors for skin disorders, antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-07-28 | — | — | US | disclosed |
| US-5089657-A | Topical antiinflammatory agents | SYNTEX (U.S.A.) INC. (US) | 1992-02-18 | — | — | US | disclosed |
| US-4786652-A | TOPICAL ADMINISTRATION | SYNTEX (U.S.A.) INC. (US) | 1988-11-22 | — | — | US | disclosed |
| EP-0282006-A1 | Naphtalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| EP-0282056-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-09-14 | — | — | EP | disclosed |
| US-4758587-A | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1988-07-19 | — | — | US | disclosed |