3,4-Dimethoxy Cinnamaldehyde

3,4-Dimethoxy Cinnamaldehyde

SCHEMBL3000359

COc1ccc(C=CC=O)cc1OC

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.72
TRPA1 O75762 1/20 0.66
MTNR1A P48039 1/20 0.66
ALDH1A1 P00352 3/20 0.66
TSHR P16473 1/20 0.66
CYP1A1 P04798 7/20 0.59
CYP1B1 Q16678 6/20 0.59
CYP1A2 P05177 4/20 0.59
TUBB4A P04350 1/20 0.59
TUBB P07437 1/20 0.59
TUBA3C P0DPH7 1/20 0.59
TUBA1B P68363 1/20 0.59
TUBA4A P68366 1/20 0.59
TUBB4B P68371 1/20 0.59
TUBB3 Q13509 1/20 0.59
TUBB2A Q13885 1/20 0.59
TUBB8 Q3ZCM7 1/20 0.59
TUBA3E Q6PEY2 1/20 0.59
TUBA1A Q71U36 1/20 0.59
TUBA1C Q9BQE3 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Dimethoxy Cinnamaldehyde SCHEMBL563071 1.00 XDH (0.72) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL1426730 0.93 XDH (0.63) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL1426731 0.93 XDH (0.63) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL6966726 0.87 XDH (0.60) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL11869754 0.87 TRPA1 (0.68) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL11869759 0.87 TRPA1 (0.68) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL6966722 0.87 XDH (0.60) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL3241265 0.85 JUN (0.71) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL9329884 0.85 TRPA1 (0.67) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL29414983 0.85 JUN (0.71) XDHTRPA1MTNR1AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 147 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781061-B2 Corrosion protection method for wellbore piping KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-10-10 US claimed
US-6566557-B2 Oxidation of a phenylpropane compound COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-05-20 US claimed
US-20020133045-A1 Process for the preparation of substituted trans-cinnamaldehyde, a natural yellow dye, from phenylpropane derivatives COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-19 US claimed
WO-2002072709-A1 A PROCESS FOR THE PREPARATION OF SUBSTITUTED TRANS-CINNAMALDEHYDE, A NATURAL YELLOW DYE, FROM PHENYLPROPANE DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-19 WO claimed
JP-9217052-A None JP disclosed
WO-2025016533-A1 NEW ENZYMES FOR THE MANUFACTURING OF 4'-O-METHYLATED PHENOLIC SUBSTANCES SYMRISE AG (DE) 2025-01-23 WO disclosed
WO-2024233598-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS YewSavin, Inc. (US) 2024-11-14 WO disclosed
US-12110453-B2 Acid injection and fracturing method for porous subterranean geological formation KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-08 US disclosed
US-12110454-B2 Downhole rock treatment method with corrosion inhibition KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-08 US disclosed
US-12104119-B2 Calcareous rock stimulation method KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2024-10-01 US disclosed
EP-4429763-A1 COMPOSITIONS AND METHODS FOR TREATING BLEEDING AND BLEEDING DISORDERS Yewsavin, Inc. (US) 2024-09-18 EP disclosed
CN-118546167-A Near infrared fluorescent dye and fluorescent composite material 复旦大学 2024-08-27 CN disclosed
EP-0946478-A1 PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS, INC. (US) 1999-10-06 EP disclosed
WO-1998029376-A1 PROCESS FOR THE SOLID PHASE SYNTHESIS OF ALDEHYDES, KETONES, OXIMES, AMINES AND HYDROXAMIC ACID COMPOUNDS RHONE-POULENC RORER PHARMACEUTICALS INC. (US) 1998-07-09 WO disclosed
JP-H09217052-A ULTRAVIOLET LIGHT ABSORBER AND SKIN PREPARATION FOR EXTERNAL USE CONTAINING THE SAME TAKASAGO INTERNATL CORP 1997-08-19 JP disclosed
US-4788206-A CARDIOVASCULAR DISORDERS, PLATELETS HOFFMANN-LA ROCHE INC. (US) 1988-11-29 US disclosed
US-4087549-A Sulphonic acid containing indenyl derivatives MERCK & CO., INC. (US) 1978-05-02 US disclosed
US-4014899-A ANTIASTHMATIC AND ANTIALLERGIC AGENTS CIBA-GEIGY CORPORATION (US) 1977-03-29 US disclosed
US-3973030-A Antiasthmatic 5,6-benzoisoindoline compositions CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3957823-A METALLIZATION BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133045-A1 Process for the preparation of substituted trans-cinnamaldehyde, a natural yellow dye, from phenylpropane derivatives CBR3, DDT, DHODH XDH 663/4885TRPA1 630/4885MTNR1A 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.