3,4-Dimethoxy Cinnamaldehyde

3,4-Dimethoxy Cinnamaldehyde

SCHEMBL563071

COc1ccc(/C=C/C=O)cc1OC

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.72
TRPA1 O75762 1/20 0.66
MTNR1A P48039 1/20 0.66
ALDH1A1 P00352 3/20 0.66
TSHR P16473 1/20 0.66
CYP1A1 P04798 7/20 0.59
CYP1B1 Q16678 6/20 0.59
CYP1A2 P05177 4/20 0.59
TUBB4A P04350 1/20 0.59
TUBB P07437 1/20 0.59
TUBA3C P0DPH7 1/20 0.59
TUBA1B P68363 1/20 0.59
TUBA4A P68366 1/20 0.59
TUBB4B P68371 1/20 0.59
TUBB3 Q13509 1/20 0.59
TUBB2A Q13885 1/20 0.59
TUBB8 Q3ZCM7 1/20 0.59
TUBA3E Q6PEY2 1/20 0.59
TUBA1A Q71U36 1/20 0.59
TUBA1C Q9BQE3 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
3,4-Dimethoxy Cinnamaldehyde SCHEMBL3000359 1.00 XDH (0.72) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL1426730 0.93 XDH (0.63) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL1426731 0.93 XDH (0.63) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL6966726 0.87 XDH (0.60) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL11869754 0.87 TRPA1 (0.68) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL11869759 0.87 TRPA1 (0.68) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL6966722 0.87 XDH (0.60) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL3241265 0.85 JUN (0.71) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL9329884 0.85 TRPA1 (0.67) XDHTRPA1MTNR1AALDH1A1TSHR
SCHEMBL29414983 0.85 JUN (0.71) XDHTRPA1MTNR1AALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 254 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11781061-B2 Corrosion protection method for wellbore piping KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-10-10 US claimed
CN-115322182-A Azole antifungal compound and application thereof 广西医科大学 2022-11-11 CN claimed
CN-108299458-B Oridonin derivative and preparation method and application thereof 青岛海洋生物医药研究院股份有限公司 2020-10-02 CN claimed
CN-103896958-A Oridonin and use of ent-6,7-open-loop kaurene type derivative thereof in preparing antituberculosis medicaments UNIV CHINA PHARMA 2014-07-02 CN claimed
US-20100292158-A1 Compositions and Methods for Enhanced Pharmacological Activity of Compositions Comprising Peptide Drug Substances IMMUPHARMA SA (FRANCE) 2010-11-18 US claimed
US-7671029-B2 Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances IMMUPHARMA SA (FR) 2010-03-02 US claimed
US-20040186058-A1 Compositions and methods for enhanced pharmacological activity of compositions comprising peptide drug substances UREKA SARL (FR) 2004-09-23 US claimed
US-6566557-B2 Oxidation of a phenylpropane compound COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-05-20 US claimed
US-20020133045-A1 Process for the preparation of substituted trans-cinnamaldehyde, a natural yellow dye, from phenylpropane derivatives COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-19 US claimed
WO-2002072709-A1 A PROCESS FOR THE PREPARATION OF SUBSTITUTED TRANS-CINNAMALDEHYDE, A NATURAL YELLOW DYE, FROM PHENYLPROPANE DERIVATIVES COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2002-09-19 WO claimed
US-6241995-B1 VACCINE TO ENHANCE IMMUNE RESPONSE UNIVERSITY OF SASKATCHEWAN (CA) 2001-06-05 US claimed
CN-1211182-A Neovascularization inhibitor KISSEI PHARMACEUTICAL (JP) 1999-03-17 CN claimed
EP-0446047-B1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1997-06-11 EP claimed
EP-0446047-A1 Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors UNILEVER PLC (GB) 1991-09-11 EP claimed
US-4402981-A ANTIULCER AGENT KALI-CHEMIE PHARMA, GMBH (DE) 1983-09-06 US claimed
US-4369309-A HYPOTENSIVE AGENTS; UASODILATION; CARDIOVASCULAR DISORDERS SS PHARMACEUTICAL CO., LTD. (JP) 1983-01-18 US claimed
JP-58008046-A None JP disclosed
JP-9217052-A None JP disclosed
US-3973030-A Antiasthmatic 5,6-benzoisoindoline compositions CIBA-GEIGY CORPORATION (US) 1976-08-03 US disclosed
US-3957823-A METALLIZATION BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020133045-A1 Process for the preparation of substituted trans-cinnamaldehyde, a natural yellow dye, from phenylpropane derivatives CBR3, DDT, DHODH XDH 663/4885TRPA1 630/4885MTNR1A 4331/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.