Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT known ✓ | P43490 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.31 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29756540 | 0.86 | CES2 (0.32) | CES2 | |
| Hydrochloric Acid SCHEMBL29573261 | 0.85 | PNMT (0.36) | HTR7SRD5A2 | |
| Hydrochloric Acid SCHEMBL29981634 | 0.84 | CES2 (0.31) | CES2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29815369 | 0.84 | MAPT (0.34) | MAPK14LMNAHTR7POLBMEN1 | |
| Hydrochloric Acid SCHEMBL29815278 | 0.84 | HSP90AA1 (0.35) | TAS1R3TAS1R1TAS1R2LMNAHTR7 | |
| Hydrochloric Acid SCHEMBL29756499 | 0.81 | ACHE (0.33) | CES2TAS1R3TAS1R1TAS1R2MEN1 | |
| Hydrochloric Acid SCHEMBL29982579 | 0.81 | ACHE (0.31) | CES2KCNK3 | |
| Hydrochloric Acid SCHEMBL29815112 | 0.79 | HSP90AA1 (0.34) | HTR7SRD5A2 | |
| Hydrochloric Acid SCHEMBL29623119 | 0.78 | NPC1 (0.43) | ALDH1A1HTR7 | |
| Hydrochloric Acid SCHEMBL31024190 | 0.78 | NPC1 (0.39) | HTR7SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3584075-B1 | LAMINATE | MITSUI CHEMICALS INC (JP) | 2024-06-05 | — | — | EP | disclosed |
| CN-111868116-B | Ethylene-alpha-olefin-nonconjugated polyene copolymer, process for producing the same, and use thereof | 三井化学株式会社 | 2022-12-09 | — | — | CN | disclosed |