Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | SDCBP | O00560 | 1/20 | 0.38 |
| ▸ | SDC2 | P34741 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30005739 | 0.90 | KMT2A (0.50) | ALDH1A1BRD9BAZ2BBAZ2ACA1 | |
| SCHEMBL30006097 | 0.83 | PARP1 (0.38) | ALDH1A1CA1CA2KMT2AHDAC1 | |
| SCHEMBL30006618 | 0.81 | CA1 (0.38) | ALDH1A1CA1CA2KMT2AHDAC1 | |
| SCHEMBL30910306 | 0.80 | NR1H4 (0.48) | CA1CA2HDAC1L3MBTL1NAMPT | |
| SCHEMBL1205128 | 0.80 | NR1H4 (0.48) | CA1CA2HDAC1L3MBTL1NAMPT | |
| SCHEMBL14979282 | 0.79 | NR1H4 (0.50) | CA1CA2HDAC1L3MBTL1NAMPT | |
| SCHEMBL30901987 | 0.79 | NR1H4 (0.50) | CA1CA2HDAC1L3MBTL1NAMPT | |
| SCHEMBL8417822 | 0.78 | HDAC1 (0.53) | CA1CA2HDAC1L3MBTL1NAMPT | |
| SCHEMBL3657504 | 0.77 | NR1H4 (0.45) | BRD9BAZ2BBAZ2ACA1CA2 | |
| SCHEMBL474132 | 0.77 | ALDH1A1 (0.53) | ALDH1A1CA1CA2KMT2AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |