Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.41 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30004674 | 0.90 | ALDH1A1 (0.46) | KMT2AALDH1A1BRD9BAZ2BBAZ2A | |
| SCHEMBL30006749 | 0.81 | KMT2A (0.45) | KMT2AALDH1A1L3MBTL1TSHRGAA | |
| SCHEMBL1205921 | 0.81 | TSHR (0.47) | ALDH1A1L3MBTL1TSHRNAMPTHDAC1 | |
| SCHEMBL7930745 | 0.80 | TSHR (0.46) | ALDH1A1L3MBTL1TSHRNAMPTHDAC1 | |
| SCHEMBL30965061 | 0.80 | TSHR (0.46) | ALDH1A1L3MBTL1TSHRNAMPTHDAC1 | |
| SCHEMBL134817 | 0.77 | ALDH1A1 (0.61) | ALDH1A1CA1CA2L3MBTL1TSHR | |
| SCHEMBL27434364 | 0.77 | L3MBTL1 (0.44) | ALDH1A1CA1CA2L3MBTL1TSHR | |
| SCHEMBL6629351 | 0.77 | ROCK2 (0.46) | L3MBTL1TSHRNAMPTGAA | |
| SCHEMBL14969490 | 0.77 | TSHR (0.57) | ALDH1A1L3MBTL1TSHRNAMPTGAA | |
| SCHEMBL30005644 | 0.77 | KMT2A (0.45) | KMT2AALDH1A1L3MBTL1TSHRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022220725-A1 | LPXH INHIBITORS AS ANTI-INFECTIVE AGENTS | ZAMARATSKI EDOUARD (SE) | 2022-10-20 | — | — | WO | disclosed |