Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 14/20 | 0.50 |
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30006916 | 0.88 | MAPK1 (0.51) | LTA4HSCN9AFPR2FFAR1 | |
| SCHEMBL27204647 | 0.88 | LTA4H (0.67) | LTA4HSCN9AFPR2LMNAKCNH2 | |
| SCHEMBL27171402 | 0.88 | LTA4H (0.67) | LTA4HSCN9AFPR2LMNAKCNH2 | |
| SCHEMBL30731680 | 0.86 | SCN9A (0.53) | LTA4HSCN9AFPR2LMNAFFAR1 | |
| SCHEMBL30689299 | 0.85 | FFAR1 (0.51) | LTA4HSCN9AFPR2LMNAFFAR1 | |
| SCHEMBL30827390 | 0.84 | LTA4H (0.52) | LTA4HSCN9AFPR2KCNH2 | |
| SCHEMBL30689322 | 0.84 | LMNA (0.47) | LTA4HSCN9AFPR2LMNAFFAR1 | |
| SCHEMBL30689380 | 0.84 | LMNA (0.54) | LTA4HSCN9AFPR2LMNAFFAR1 | |
| SCHEMBL29123397 | 0.81 | SCN9A (0.54) | LTA4HSCN9AFPR2LMNAKCNH2 | |
| SCHEMBL29123393 | 0.81 | SCN9A (0.54) | LTA4HSCN9AFPR2LMNAKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4323062-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | Novartis AG (CH) | 2024-02-21 | — | — | EP | disclosed |
| WO-2022219546-A1 | HETEROARYL AMINOPROPANOL DERIVATIVES AS INHIBITORS OF LTA4H | NOVARTIS AG (CH) | 2022-10-20 | — | — | WO | disclosed |